“…Infection most often arises in a diseased aorta, either in a preexisting aneurysm, at the site of an atherosclerotic plaque, or at the site of some accidental or iatrogenic aortic trauma. Indeed, infected thoracic aortic aneurysms may arise as a late complication of cardiac surgery, often associated with postoperative mediastinitis, typically at the sites of aortic cannulation or anastomotic suture lines (200,201).…”