Myelin-forming ability of Schwann cell-like cells induced from rat adipose-derived stem cells in vitro

Xu, Yongfeng; Liu, Lan; Li, Yong; Zhou, Chang; Xiong, Fu; Liu, Zhengshan; Gu, Rong; Hou, Xiaomei; Zhang, Cheng

doi:10.1016/j.brainres.2008.08.088

Cited by 121 publications

(86 citation statements)

References 21 publications

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“…These cells may prove beneficial for the treatment of peripheral and central nerve injuries. 7 Kim et al reported that human ASCs significantly improved motor recovery and enhanced morphometric change when implanted in contusive spinal cord injuries in rats. 8 …”

Section: Introductionmentioning

confidence: 99%

Adipogenesis of Human Adipose-Derived Stem Cells Within Three-Dimensional Hollow Fiber-Based Bioreactors

Gerlach

Lin²,

Brayfield³

et al. 2012

Tissue Engineering Part C: Methods

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Section: Introductionmentioning

confidence: 99%

Adipogenesis of Human Adipose-Derived Stem Cells Within Three-Dimensional Hollow Fiber-Based Bioreactors

Gerlach

Lin²,

Brayfield³

et al. 2012

Tissue Engineering Part C: Methods

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“…The extracted cells also expand more rapidly than those from other tissues [11]. We and other groups have shown that rat ASC can be differentiated toward a Schwann cell-like phenotype which promotes neurite outgrowth [12][13][14][15][16] and myelination [16][17][18]. In addition to their ability to differentiate, ASC can secrete a plethora of growth factors that can mediate angiogenesis, wound healing, tissue regeneration, and immune cell reactions [19,20].…”

mentioning

confidence: 99%

Stimulating the Neurotrophic and Angiogenic Properties of Human Adipose-Derived Stem Cells Enhances Nerve Repair

Kingham

Kolar

Novikova

et al. 2014

Stem Cells and Development

187

147

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“…Nowadays it is known that the ADSCs have the ability to form consistent cells as neurons 5 , Oligodendrocytes 6 , Schwann cells 7,8 and epidermal cell lineage 9 .…”

Section: Introductionmentioning

confidence: 99%

Adipose-derived stem cells (ADSC) in the viability of random skin flap in rats

et al. 2014

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Purpose: To evaluate the effects of the adipose-derived stem cells (ADSC) in the viability of random skin flap in rats.Methods: Thirty five adult male Wistar rats (weight 250-300 g) were used. ADSC were isolated from adult male rats (n=5). ADSC were separated, cultured and then analyzed. A dorsal skin flap measuring 10x4 cm was raised and a plastic barrier was placed between the flap and its bed. After the surgical procedure, the animals were randomized into two groups (n=15 each group), group control and group ADSC. In all groups the procedures were performed immediately after the surgery. The percentage of flap necrosis was measured on the seventh postoperative day. Results:The ADSC were able to replicate in our culture conditions. We also induced their adipogenic, osteogenic and chondrogenic differentiation, verifying their mesenchymal stem cells potentiality in vitro. The results were statistically significant showing that the ADSC decreased the area of necrosis (p<0.05). Conclusion:The cells demonstrated adipogenic, osteogenic and chondrogenic differentiation potential in vitro. The administration of adipose-derived stem cells was effective to increase the viability of the random skin flaps in rats.

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Myelin-forming ability of Schwann cell-like cells induced from rat adipose-derived stem cells in vitro

Cited by 121 publications

References 21 publications

Adipogenesis of Human Adipose-Derived Stem Cells Within Three-Dimensional Hollow Fiber-Based Bioreactors

Adipogenesis of Human Adipose-Derived Stem Cells Within Three-Dimensional Hollow Fiber-Based Bioreactors

Stimulating the Neurotrophic and Angiogenic Properties of Human Adipose-Derived Stem Cells Enhances Nerve Repair

Adipose-derived stem cells (ADSC) in the viability of random skin flap in rats

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