Myeloid sarcoma of the vulva as the presenting symptom in a patient with acute myeloid leukemia

Myeloid sarcoma of the vulva as the initial presentation of acute myeloid leukaemia

“…Previously, Ers ßahin et al described an elderly woman with myeloid sarcoma of the vulva as the initial presentation of AML. 10 In contrast to our patient, the tumour in the previous report occurred mainly on the skin of the labia majora, not the vulvar mucosa. Moreover, there was no prior history of myelodysplastic syndrome or other haematological diseases in the previous case.…”

Myeloid Sarcoma Of Vulva: A Short Update

“…1, 2 and 3). Case reported by Ersahin et al [3] also had synchronous Paget's disease and infiltrating ductal adenocarcinoma of right breast. Case reported by Hu et al [7] had extensive myeloid sarcoma involving bilateral peri-renal spaces, ureters and adnexae.…”

“…4 and 5) or associated medullary (case no. 2 and 6) involvement [2][3][4][5]. Cases who relapsed at the vulva (case no.…”

“…Two patients-case no. 1 and 6 died during follow up due to sepsis and disease relapse respectively [3,7].…”

Vulvar sarcomas: Short guideline for histopathological recognition and clinical management. Part 2

“…23 Their localization on the female genitalia is extremely rare, with few cases reported -mainly in the vagina and vulva. 24 Myeloid sarcomas can occur in up to 1.4% of patients with acute myeloid leukemia (AML), and 1.1% of patients with high-risk myelodysplastic syndrome in transformation to AML. 25 Their appearance is associated with a number of chromosomal aberrations, including trisomy 8, trisomy 4, monosomy 7, 16q-, 5q-, 20q-, and trisomy 11.…”