2012
DOI: 10.1007/s12291-012-0220-0
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Myeloperoxidase: A New Twist to an Old Tale

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Cited by 6 publications
(3 citation statements)
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“…Neutrophils are undoubtedly major effectors of acute and chronic inflammation. Consequently, a common feature between these diseases is chronic neutrophilic inflammation, as evidenced by an exacerbated and sustained infiltration of neutrophils into the lungs with concurrent neutrophilic leukocytosis ( Gernez et al , 2010 , Anand and Anand, 2012 ).…”
mentioning
confidence: 99%
“…Neutrophils are undoubtedly major effectors of acute and chronic inflammation. Consequently, a common feature between these diseases is chronic neutrophilic inflammation, as evidenced by an exacerbated and sustained infiltration of neutrophils into the lungs with concurrent neutrophilic leukocytosis ( Gernez et al , 2010 , Anand and Anand, 2012 ).…”
mentioning
confidence: 99%
“…Por lo tanto, podría ser un marcador que relacione el estrés oxidativo, la inflamación, la disfunción endotelial y el riesgo trombogénico, a la vez que confirma la importancia de los neutrófilos en la fisiopatología de la aterosclerosis. 46 La actividad excesiva de la MPO puede inducir daño a tejidos por la producción de oxidantes y, consecuentemente, formar especies reactivas de lípidos y proteínas. En estudios recientes se ha demostrado que la exposición de lipoproteínas de baja densidad (LDL) a leucocitos activados produce, a través de la MPO, especies nitrogenadas y halogenadas que facilitan procesos de peroxidación lipídica, nitración proteica y conversión a formas proaterogénicas de LDL en la pared vascular.…”
Section: Proteínas Con Actividad Oxidante: Nqo1 Y Mieloperoxidasaunclassified
“…Infusion of glucose to rats that were suffering from severe lung injury served as a source of H 2 O 2 and MPO (Figure 3). 115 In kidney diseases, MPO acts as an important factor in tubule-interstitial and glomerular diseases. Several studies have reported that MPO has a role in renal disorders.…”
Section: Mpo Role In Spinal Cord Injurymentioning
confidence: 99%