Myocardial dysfunction in patients with aortic stenosis and hypertensive heart disease assessed by MR tissue phase mapping

Knobelsdorff‐Brenkenhoff, Florian von; Hennig, Pierre; Menza, Marius; Dieringer, Matthias A.; Foell, Daniela; Jung, Bernd; Schulz‐Menger, Jeanette

doi:10.1002/jmri.25125

Cited by 10 publications

(19 citation statements)

References 35 publications

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“…In this context, 2D cine phase contrast MRI with three-directional velocity encoding, termed tissue phase mapping (TPM), is a well-established technique to quantify LV regional myocardial velocities (24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41) but has rarely been applied to the RV. In 2000, Kayser et al (6) analyzed RV wall motion with TPM for the first time, and more recently biventricular function in healthy adults (42) and adult patients with pulmonary hypertension (43) have been investigated.…”

Section: Introductionmentioning

confidence: 99%

Impact of age and cardiac disease on regional left and right ventricular myocardial motion in healthy controls and patients with repaired tetralogy of fallot

Ruh

Sarnari

Berhane

et al. 2019

Int J Cardiovasc Imaging

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Purpose-The assessment of both left (LV) and right ventricular (RV) motion is important to understand the impact of heart disease on cardiac function. The MRI technique of tissue phase mapping (TPM) allows for the quantification of regional biventricular three-directional myocardial velocities. The goal of this study was to establish normal LV and RV velocity parameters across a wide range of pediatric to adult ages and to investigate the feasibility of TPM for detecting impaired regional biventricular function in patients with repaired tetralogy of Fallot (TOF). Methods-36 healthy controls (age=1-75 years) and 12 TOF patients (age=5-23 years) underwent cardiac MRI including TPM in short-axis locations (base, mid, apex). For ten adults, a second TPM scan was used to assess test-retest reproducibility. Data analysis included the calculation of biventricular radial, circumferential, and long-axis velocity components, quantification of systolic and diastolic peak velocities in an extended 16+10 LV+RV segment model, and assessment of inter-ventricular dyssynchrony.

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Section: Introductionmentioning

confidence: 99%

Impact of age and cardiac disease on regional left and right ventricular myocardial motion in healthy controls and patients with repaired tetralogy of fallot

Ruh

Sarnari

Berhane

et al. 2019

Int J Cardiovasc Imaging

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“…In contrast, we found significantly reduced regional diastolic peak velocities again in the basal lateral wall of DD+. Von Knobelsdorff‐Brenkenhoff et al 15 . and Foell et al 13 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques

et al. 2020

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Aims Heart failure with preserved ejection fraction is still a diagnostic and therapeutic challenge, and accurate non-invasive diagnosis of left ventricular (LV) diastolic dysfunction (DD) remains difficult. The current study aimed at identifying the most informative cardiovascular magnetic resonance (CMR) parameters for the assessment of LVDD. Methods and results We prospectively included 50 patients and classified them into three groups: with DD (DD+, n = 15), without (DDÀ, n = 26), and uncertain (DD±, n = 9). Diagnosis of DD was based on echocardiographic E/E′, invasive LV end-diastolic pressure, and N-terminal pro-brain natriuretic peptide. CMR was performed at 1.5 T to assess LV and left atrial (LA) morphology, LV diastolic strain rate (SR) by tissue tracking and tagging, myocardial peak velocities by tissue phase mapping, and transmitral inflow profile using phase contrast techniques. Statistics were performed only on definitive DD+ and DDÀ (total number 41). DD+ showed enlarged LA with LA end-diastolic volume/height performing best to identify DD+ with a cutoff value of ≥0.52 mL/cm (sensitivity = 0.71, specificity = 0.84, and area under the receiver operating characteristic curve = 0.75). DD+ showed significantly reduced radial (inferolateral E peak: DDÀ: À14.

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“…More important, the very short breath‐hold time (eight heartbeats) compared to previous studies (13–28 heartbeats) may allow this technology to be used more widely. Specifically, it would be better suited to exercise studies and used in patients unable to perform long breath‐holds (sick adults and children).…”

Section: Discussionmentioning

confidence: 99%

Rapid breath‐hold assessment of myocardial velocities using spiral UNFOLD‐ed SENSE tissue phase mapping

Kowalik

Muthurangu

Khushnood

et al. 2016

Magnetic Resonance Imaging

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Myocardial dysfunction in patients with aortic stenosis and hypertensive heart disease assessed by MR tissue phase mapping

Abstract: Even with preserved left ventricle (LV) ejection fraction, peak longitudinal and radial velocities of the LV are reduced in AS and HYP, indicating early functional impairment. J. Magn. Reson. Imaging 2016;44:168-177.

Cited by 10 publications

References 35 publications

Impact of age and cardiac disease on regional left and right ventricular myocardial motion in healthy controls and patients with repaired tetralogy of fallot

Impact of age and cardiac disease on regional left and right ventricular myocardial motion in healthy controls and patients with repaired tetralogy of fallot

Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques

Rapid breath‐hold assessment of myocardial velocities using spiral UNFOLD‐ed SENSE tissue phase mapping

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