Myocardial Inury: An Unrecognized Complication of Cerebral Malaria

Abstract

Letters to the Editor bodies in the bone marrow or splenic aspiration is most important in these cases, confirming the diagnosis.

Acute myocardial infarction in a hospital cohort of malaria

“…Although this observation does not imply a cause-effect relationship, temporal changes over the four years and a possible biological explanation from the previous studies[367] suggest that malaria could have been the cause of the higher occurrence of AMI in this group. We provide the first study in a hospital setting, demonstrating the cardiac complications, that is, acute myocardial infarction, in malaria.…”

“…[3679] Adhesion of parasitized red blood cells to the endothelium of myocardial capillaries has been shown in monkeys and man. [39] Ischemia, acidosis, toxic effects of substances similar to P. falciparum glycosyl-phosphatidyl-inositol or Plasmodium-triggered mechanisms such as apoptosis may be responsible for myocardial damage. [6] Raised catecholamine has been found in malaria, which may induce vasoconstriction, resulting in myocardial damage.…”

“…[6] Raised catecholamine has been found in malaria, which may induce vasoconstriction, resulting in myocardial damage. [3]…”

Acute myocarditis in vivax malaria: an extremely rare complication

“…4 Mohapatra et al described myocardial injury as evidenced by raised cardiac troponin T levels in 11.8% patients with cerebral malaria. 5 The present case had haematological involvement in the form of pancytopenia and cardiac involvement. However, cerebral involvement and hypoglycaemia were lacking.…”

Atypical manifestations of malaria

“…In a study carried out by Mohapatra et al, of 110 patients with cerebral malaria, 13 (11.8%) had myocardial injury as evidenced by raised cardiac troponin T levels. 88 Of these 13 patients, 7 died within 72 h and 3 on 9th day of hospitalization. Autopsy revealed diffuse myocardial injury in three cases.…”