Myocardial performance is impaired in patients with branch retinal vein occlusion

Kaderli, Berkant; Kaderli, Aysel Aydin; Güllülü, Sümeyye; İnan, Ümit Übeyt; Şentürk, Tunay; Aydınlar, Ali; Yucel, Ahmet Ali; Avcı, Remzi

doi:10.1177/0300060514543038

Cited by 6 publications

(11 citation statements)

References 37 publications

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“…This finding correlates with the study by Kaderli et al that states that myocardial function is impaired in patients with BRVO. 13 We therefore speculate that poor presenting visual acuity in RVO is a consequence of relative retinal ischemia attributable to carotid narrowing evidenced by association with higher IC PSV and IC to CC PSV ratio. In addition, the TMV in patients with CRVO was higher in those with larger ventricular diameter at the end of systole.…”

Section: Quantitative Carotid Doppler and Cardiac Echography In Rvomentioning

confidence: 77%

“…1,11 Association of retinal vascular changes with increased risk of cardiovascular dysfunction has been brought out in other studies as well. 5,12,13,14 Song and colleagues have shown that retinal vascular analysis has good predictive value in identifying atherosclerosis of the carotid artery in asymptomatic patients. 15 The severity of coronary disease may also be estimated by retinal vascular analysis, and myocardial performance is known to be decreased in patients with BRVO.…”

Section: Discussionmentioning

confidence: 99%

“…15 The severity of coronary disease may also be estimated by retinal vascular analysis, and myocardial performance is known to be decreased in patients with BRVO. 13,16 Studies have shown that detection of carotid plaques and thickness of the intima-media complex by Doppler imaging is a useful cardiovascular risk assessment method. 17,18 In the same manner, Chawluk and colleagues have demonstrated the importance of carotid Doppler analysis in retinal ischemic syndromes.…”

Section: Discussionmentioning

confidence: 99%

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Relationship of Echocardiography and Carotid Doppler With Macular Parameters in Retinal Vein Occlusions: A Retrospective Analysis

Madanagopalan

Singh

2017

Journal of VitreoRetinal Diseases

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Aim: To find the relationship of cardiac dimensions and valvular flow rates in echocardiography and carotid parameters in Doppler imaging with macular variables in retinal vein occlusions (RVOs) and to identify macular parameters in RVO that may predict cardiovascular morbidity. Methods: A retrospective observational study was done with 17 patients with central RVO (CRVO) and 13 patients with branch RVO (BRVO). Best-corrected distance visual acuity (BCVA) and spectral domain optical coherence tomography parameters such as central macular volume (CMV) and total macular volume (TMV) were noted. Details of echocardiography and carotid Doppler were retrieved. Relationship of BCVA, CMV, and TMV with cardiac dimensions and valvular flow rates and carotid flow velocities was analyzed. Results: Correlation showed significant association between BCVA and ipsilateral internal carotid (IC) to common carotid (CC) peak systolic velocity (PSV) ratio in eyes with CRVO and BRVO (r ¼ .50, P ¼ .04, and r ¼ .64, P ¼ .02, respectively). Significant association of TMV and left ventricular end systolic diameter (LVs) was seen in CRVO (r ¼ .69, P ¼ .002). Association was also noted between higher IC PSV and poor BCVA, higher IC to CC PSV ratio to poor BCVA, and larger LVs with higher TMV (P < .03 for all). In patients with BRVO, association was noted between higher IC to CC PSV ratio to poor BCVA, lesser ejection fraction (EF) with poor BCVA, and lesser EF with higher CMV (P < .03 for all). Conclusions: In our study eyes with RVO, decreased BCVA was related to carotid narrowing. Decreased BCVA in BRVO was also related to decreased EF. Consistently larger macular volumes in our study eyes with RVO were related to suboptimal cardiac function identified by larger end systolic diameters and lesser EF. Our pilot study has thus showed that a quantitative relationship exists between macular parameters and cardiovascular variables in RVO.

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Section: Quantitative Carotid Doppler and Cardiac Echography In Rvomentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Relationship of Echocardiography and Carotid Doppler With Macular Parameters in Retinal Vein Occlusions: A Retrospective Analysis

Madanagopalan

Singh

2017

Journal of VitreoRetinal Diseases

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“…15 Although the state of endothelial dysfunction is not known in patients with RVO, it has been reported that the ejection fraction is signi cantly lower, and suboptimal cardiac functions are associated with larger systolic diameters in cardiac structures. 16 It has been reported that patients with BRVO have myocardial dysfunction, and these patients may need monitoring in terms of CAD 17 . It has been shown that the severity of coronary diseases and myocardial performance can be estimated by a retinal vascular analysis.…”

Section: Discussionmentioning

confidence: 99%

Retinal Vein Occlusion: A Form of Local Venous Thrombosis or a Result of Systemic Endothelial Dysfunction

Bozkurt

Çetin

Rencüzoğulları

2021

Preprint

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Background: To determine the condition of systemic endothelial function and carotid intima media thickness (CIMT) in patients with retinal vein occlusion (RVO) and to identify the risk factors associated with the disease.Methods: Seventy-six patients who presented to the clinic with the diagnosis of RVO and 76 age- and gender-matched healthy individuals without a RVO history were included in the study. The patients' vision levels and central macular thickness were measures, and diabetes, hypertension, hyperlipidemia, carotid artery disease, body mass index and smoking histories were recorded. The endothelial function levels of the patients, pulse wave velocity (PWV), and CIMT were measured. Serum hematological parameters were evaluated.Results: The most important risk factor in patients with RVO was found to be hypertension (OR 1.455, 95% CI 1.981-9.272; p=0.001) compared to the control group, and diabetes (OR 0.460, 95% CI 1.981-9.272; p=0.001) and hyperlipidemia (OR 0.124, 95% CI 0.371-3.456; p=0.828) were significantly more common among the patients.There was a statistically significant difference between the RVO and control groups in terms of flow-mediated dilation (OR 0.050, 95% CI 0.020-0.080; p =0.001), PWV (OR 0.392, 95% CI 0.271-0.513; p<0.001), and the CIMT of both sides (OR 2.434, 95% CI 1.801-3.055 for the right CIMT and OR 2.284, 95% CI 1.646-2.922 for the left CIMT) (p<0.001 for all).Conclusion: Considering that RVO is associated with systemic endothelial dysfunction and may also be accompanied by carotid artery stenosis, we think that additional systemic diseases should be questioned in this patient group.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Systemic Endothelial Dysfunction in Patients with Retinal Vein Occlusion

Bozkurt¹,

Çetin²,

Rencüzoğulları³

2021

Preprint

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Purpose: To determine the condition of systemic endothelial function and carotid intima media thickness (CIMT) in patients with retinal vein occlusion (RVO) and to identify the risk factors associated with the disease.Material-Method: Seventy-six patients who presented to the clinic with the diagnosis of RVO and 76 age- and gender-matched healthy individuals without a RVO history were included in the study. The patients' vision levels and central macular thickness were measures, and diabetes, hypertension, hyperlipidemia, carotid artery disease, body mass index and smoking histories were recorded. The endothelial function levels of the patients, pulse wave velocity (PWV), and CIMT were measured. Serum hematological parameters were evaluated.Results: The most important risk factor in patients with RVO was found to be hypertension (OR 1.455, 95% CI 1.981-9.272; p=0.001) compared to the control group, and diabetes (OR 0.460, 95% CI 1.981-9.272; p=0.001) and hyperlipidemia (OR 0.124, 95% CI 0.371-3.456; p=0.828) were significantly more common among the patients.There was a statistically significant difference between the RVO and control groups in terms of flow-mediated dilation (OR 0.050, 95% CI 0.020-0.080; p =0.001), PWV (OR 0.392, 95% CI 0.271-0.513; p<0.001), and the CIMT of both sides (OR 2.434, 95% CI 1.801-3.055 for the right CIMT and OR 2.284, 95% CI 1.646-2.922 for the left CIMT) (p<0.001 for all).Conclusion: Considering that RVO is associated with systemic endothelial dysfunction and may also be accompanied by carotid artery stenosis, we think that additional systemic diseases should be questioned in this patient group.

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Myocardial performance is impaired in patients with branch retinal vein occlusion

Abstract: Myocardial performance is decreased in patients with BRVO, independent of whether or not they have hypertension.

Cited by 6 publications

References 37 publications

Relationship of Echocardiography and Carotid Doppler With Macular Parameters in Retinal Vein Occlusions: A Retrospective Analysis

Relationship of Echocardiography and Carotid Doppler With Macular Parameters in Retinal Vein Occlusions: A Retrospective Analysis

Retinal Vein Occlusion: A Form of Local Venous Thrombosis or a Result of Systemic Endothelial Dysfunction

Evaluation of Systemic Endothelial Dysfunction in Patients with Retinal Vein Occlusion

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