Myocardial Viability Imaging: Does It Still Have a Role in Patient Selection Prior to Coronary Revascularisation?

Grover, Suchi; Srinivasan, Govindarajan; Selvanayagam, Joseph B.

doi:10.1016/j.hlc.2012.03.008

Cited by 7 publications

(8 citation statements)

References 74 publications

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“…In 2007 a prospective cohort trial (29 patients) demonstrated that LGE-CMR and PET/SPECT were equally effective in determining myocardial viability [43]. Furthermore, several studies have supported the latter finding and have additionally demonstrated that LGE-CMR is superior to DSE in certain patients, including those with poor images or arrhythmias for the detection of viability [25], [44].…”

Section: Imaging Techniques Employed For Viability Assessmentmentioning

confidence: 97%

“…In addition, a study by Bove et al demonstrated a similar improvement in percentage of wall thickness and LV function with low dose dobutamine in segments with 1–50% transmural infarction after revascularization [23]. Other studies suggested that the combination of LGE and low dose dobutamine stress CMR may offer a more reliable method of assessing myocardial viability [24], [25]. A recent study demonstrated that combination of CMR viability parameters, contractile reserve by low dose dobutamine, EDWT and scar quantification improved the prediction of function recovery [26].…”

Section: Imaging Techniques Employed For Viability Assessmentmentioning

confidence: 98%

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Non-invasive imaging in detecting myocardial viability: Myocardial function versus perfusion

Elfigih

Henein

2014

IJC Heart & Vasculature

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Coronary artery disease (CAD) is the most prevalent and single most common cause of morbidity and mortality [1] with the resulting left ventricular (LV) dysfunction an important complication. The distinction between viable and non-viable myocardium in patients with LV dysfunction is a clinically important issue among possible candidates for myocardial revascularization. Several available non-invasive techniques are used to detect and assess ischemia and myocardial viability. These techniques include echocardiography, radionuclide images, cardiac magnetic resonance imaging and recently myocardial computed tomography perfusion imaging. This review aims to distinguish between the available non-invasive imaging techniques in detecting signs of functional and perfusion viability and identify those which have the most clinical relevance in detecting myocardial viability in patients with CAD and chronic ischemic LV dysfunction. The most current available studies showed that both myocardial perfusion and function based on non-invasive imaging have high sensitivity with however wide range of specificity for detecting myocardial viability. Both perfusion and function imaging modalities provide complementary information about myocardial viability and no optimum single imaging technique exists that can provide very accurate diagnostic and prognostic viability assessment. The weight of the body of evidence suggested that non-invasive imaging can help in guiding therapeutic decision making in patients with LV dysfunction.

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Section: Imaging Techniques Employed For Viability Assessmentmentioning

confidence: 97%

Section: Imaging Techniques Employed For Viability Assessmentmentioning

confidence: 98%

Non-invasive imaging in detecting myocardial viability: Myocardial function versus perfusion

Elfigih

Henein

2014

IJC Heart & Vasculature

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“…28 Furthermore, several studies demonstrated the superiority of DE-MRI to dobutamine stress echocardiography in patients with arrhythmias. 29…”

Section: The Assessment Of Myocardial Viability With Mrimentioning

confidence: 99%

Magnetic Resonance Imaging of Myocardial Function Following Intracoronary and Intramyocardial Stem Cell Injection

Mester

Oltean-Péter

Rodean³

et al. 2017

Journal of Interdisciplinary Medicine

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Stem cell-based therapy is a new therapeutic option that can be used in patients with cardiac diseases caused by myocardial injury. Cardiac magnetic resonance imaging (MRI) is a new noninvasive imaging method with an increasingly widespread indication. The aim of this review was to evaluate the role of cardiac MRI in patients with myocardial infarction undergoing stem cell therapy. We studied the role of MRI in the assessment of myocardial viability, stem cell tracking, assessment of cell survival rate, and monitoring of the long-term effects of stem cell therapy. Based on the current knowledge in this field, this noninvasive, in vivo cardiac imaging technique has a large indication in this group of patients and plays an important role in all stages of stem cell therapy, from the indication to the long-term follow-up of patients.

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“…TEE should be considered in patients with ESUS given its higher detection rate of valvular abnormalities including vegetation’s left atrial and ventricular thrombus, left atrial enlargement, and evaluation of the aortic arch irrespective of patients age ( 12 ). The utility of Cardiac MRI (CMRI) becomes important in detecting a cryptogenic source of stroke due to its overall greater sensitivity and high specificity in detecting LV thrombi, especially in the post MI sub-population ( 56 , 57 ). CMRI is a multimodal technique utilizing a diverse subset of imaging such as spin echo, gradient echo as well as flow velocity encoding sequences giving enhanced resolution of cardiac anatomy ( 58 ).…”

Section: Possible Etiologies Of Esus and Csmentioning

confidence: 99%

Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice

et al. 2016

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Up to a third of strokes are rendered cryptogenic or of undetermined etiology. This number is specifically higher in younger patients. At times, inadequate diagnostic workups, multiple causes, or an under-recognized etiology contributes to this statistic. Embolic stroke of undetermined source, a new clinical entity particularly refers to patients with embolic stroke for whom the etiology of embolism remains unidentified despite through investigations ruling out established cardiac and vascular sources. In this article, we review current classification and discuss important clinical considerations in these patients; highlighting cardiac arrhythmias and structural abnormalities, patent foramen ovale, paradoxical sources, and potentially under-recognized, vascular, inflammatory, autoimmune, and hematologic sources in relation to clinical practice.

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Myocardial Viability Imaging: Does It Still Have a Role in Patient Selection Prior to Coronary Revascularisation?

Cited by 7 publications

References 74 publications

Non-invasive imaging in detecting myocardial viability: Myocardial function versus perfusion

Non-invasive imaging in detecting myocardial viability: Myocardial function versus perfusion

Magnetic Resonance Imaging of Myocardial Function Following Intracoronary and Intramyocardial Stem Cell Injection

Embolic Strokes of Unknown Source and Cryptogenic Stroke: Implications in Clinical Practice

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