Myopericytoma of the kidney

Lau, Sean K.; Klein, Roman; Jiang, Zhong; Weiss, Lawrence M.; Chu, Peiguo

doi:10.1016/j.humpath.2010.02.014

Cited by 44 publications

(43 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Myopericytoma is a rare neoplasm that generally arises from skin and superficial soft tissue of the distal extremities and is particularly rare in the visceral organs [1]. With increased clinical recognition, a wider distribution has been described; however, a heart lesion has never previously been reported, so this report further expands the list of locations.…”

mentioning

confidence: 79%

Primary benign myopericytoma of the left atrium

et al. 2016

View full text Add to dashboard Cite

A 46-year-old woman presented with progressive dyspnea. Physical examination revealed a blood pressure of 140/60 mmHg, a heart rate of 80 bpm and respiration of 16 breaths/min. Heart sounds were regular and distant. No murmurs or rubs were noted. Jugular venous pressure was normal. Lungs were clear, abdomen soft and no peripheral edema was found. The electrocardiogram and the chest X-ray film were normal. Two-dimensional transthoracic echocardiography revealed a large left atrial (LA) mass (31 9 40 9 45 mm), above the mitral valve, and seemingly attached to the posterior wall of the left atrium with a wide pedicle (Fig. 1a, b; Video 1 and 2). Moderate mitral stenosis due to the diastolic obstruction by the tumor and mild mitral regurgitation was observed (Video 3). Mean transmitral gradient was 12 mmHg and mitral valve area was 1.4 cm 2 . Transesophageal echocardiography did not add any additional information. A diagnosis of atrial myxoma was made. The patient underwent surgical removal of the mass. At the time of surgery, the tumor had a smooth surface and a rubbery consistency (Fig. 1c). It was found attached in the LA floor without involvement of either the pulmonary veins or the mitral valve. The tumor was shaved off the atrium. The surgeon decided not to resect the tumor en bloc due to the risk of bleeding in the reconstruction of the floor of the LA. Serial sectioning showed areas of focal necrosis. Histopathologic and immunophenotypic features revealed a primary cardiac benign myopericytoma (Fig. 1d). The patient underwent FDG PET/CT imaging of the chest, abdomen and pelvis, and extracardiac metastases were ruled out. The patient did well and was ultimately discharged home. A follow-up echocardiogram at 24 months disclosed no abnormalities.

show abstract

mentioning

confidence: 79%

Primary benign myopericytoma of the left atrium

et al. 2016

View full text Add to dashboard Cite

show abstract

“…A myopericytoma is a type of the pericytic neoplasms that grows with a pericytomatous appearance with neoplastic cells arranged in a concentric multilayered fashion surrounding the blood vessels and the dilated branching vascular lumina. One recent study reported a strong expression of CD34 [39] in such a tumor. Paraganglioma is composed histologically of a well-circumscribed mass composed of nested growth pattern of tumor cells known as Zellballen pattern, with a highly vascularized fibrous stroma.…”

Section: Discussionmentioning

confidence: 99%

Glomangioma of the Kidney: A Rare Case of Glomus Tumor and Review of the Literature

Almaghrabi

Al-Maghrabi

2017

Case Reports in Pathology

View full text Add to dashboard Cite

Background Glomus tumors are rare mesenchymal tumors originating from glomus bodies in the skin. Glomus tumors of the kidney are rare tumors and only a few cases have been reported in the medical literature. An extensive search revealed a very limited number of primary renal glomus tumors. Although most of these cases were benign in nature, including a case with uncertain diagnosis of malignant potential, two were malignant. Case Report We present a unique case of a 57-year-old male patient with an incidentally discovered 2 cm left renal mass. Histopathology examination and immunohistochemical studies confirm the diagnosis of glomangioma (a form of glomus tumor). The patient was followed for one year after partial nephrectomy and showed a benign course without any evidence of local recurrence or metastasis. Conclusion To the best of our knowledge, this is the 16th case of primary benign renal glomus tumors. Primary renal glomus tumors are rare and may mimic other mesenchymal renal neoplasms radiologically. Proper investigation (including histopathological analysis and immunohistochemical staining) of kidney tumors is essential to make the diagnosis of glomus tumors, which usually show a benign clinical course following resection.

show abstract

“…Myopericytoma is a rare neoplasm that commonly arises from the skin and superficial soft tissues of the distal extremities, including the trunk, head and neck regions (1–4). In the majority of cases, myopericytoma is generally <4 cm in diameter, and its occurrence is particularly rare in the visceral organs.…”

Section: Discussionmentioning

confidence: 99%

“…Myopericytoma is a rare neoplasm that commonly arises from the skin and superficial soft tissues of distal extremities, and is particularly rare in the visceral organs (1). The present case of giant myopericytoma showing kidney involvement is an extremely rare occurrence.…”

Section: Introductionmentioning

confidence: 99%

“…Myopericytoma demonstrates special morphological features composed of myoid-appearing oval or spindle-shaped cells with a concentric perivascular arrangement (1–3). In addition, myopericytoma exhibits immunoreactivity for muscle-specific and smooth muscle actin (1–4). The current report presents a case of renal myopericytoma, and a related literature review was performed to analyze the disease.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Renal myopericytoma: A case report with a literature review

Zhang

Shi

et al. 2013

Oncology Letters

View full text Add to dashboard Cite

Myopericytoma is a rare neoplasm that generally arises from the skin and superficial soft tissues of distal extremities, and is particularly rare in the visceral organs. The current report presents a case of giant myopericytoma showing kidney involvement, which is extremely rare. A 39-year-old male presented to the Department of Urology with a 2-month history of a painless and palpable mass in the region of the left abdomen. Unenhanced computed tomography revealed a 9×10×18-cm3 mass that was heterogeneous with central lower density. The patient underwent radical nephrectomy, including lymphadenectomy, without adjuvant therapy. The tumor was composed of spindle-shaped myoid cells with a concentric arrangement and showed immunoreactivity for smooth muscle actin and cluster of differentiation (CD)10, and had a Ki-67 index of <1%; however, staining was negative for CD34, desmin, S-100 protein, cytokeratin, human melanoma black (HMB)-45, B-cell lymphoma (Bcl)-2 and CD99. Routine follow-up revealed no local or distant metastatic signs of reccurrence for 20 months. The present report shows that renal myopericytoma may be a benign tumor, and surgical excision without adjuvant therapy may be the only potentially curative treatment approach.

show abstract

Myopericytoma of the kidney

Cited by 44 publications

References 23 publications

Primary benign myopericytoma of the left atrium

Primary benign myopericytoma of the left atrium

Glomangioma of the Kidney: A Rare Case of Glomus Tumor and Review of the Literature

Renal myopericytoma: A case report with a literature review

Contact Info

Product

Resources

About