Myxoma of ovary: an uncommon entity

Abstract

Ovarian myxoma is a rare but distinct entity and this should be differentiated from the other lesions of ovary with myxoid changes.

Myxoid Degeneration of Ovarian Tumor in Young Patient, Laparoscopic Approach

“…Myxoid degenerated ovarian tumors can be malignant transformed into myxoid leiomyosarcomas of the ovary with extremely metastatic possibilities [3]. Assiduous atomic history, proper laboratory and imaging findings consist of the gold standard of therapeutic mapping Myxoid degeneration of the ovary consists of a rare entity, especially in premenopausal patients [1]. Due to various ovarian alterations, differential diagnosis of such tumors is mandatory.…”

Myxoma of the Ovary

“…Ovarian myxoma is quite a rare condition that is a rare entity ( 2 ). Histologically, these tumors are produced from the cells in a random sequence in a myxoid matrix without an infiltrative growth pattern, mitotic activity, cytological atypia or necrosis ( 3 , 4 ).…”

“…The differential diagnosis of ovarian myxomas with other ovarian myxoid lesions should be performed. The differential diagnosis includes angio-myxomas, fibromas with widespread myxoid degeneration, and primary ovarian stromal lesions containing high amounts of myxoid matrix, such as massive edema, or non-ovarian stromal lesions that are generally maligned ( 2 , 5 ). In massive edema of the ovaries, the normal residual ovarian stromal and intercellular structures together with the mucin negativity in connective tissue are observed around the edematous tissue.…”

“…In aggressive angio-myxomas, there are infiltrative borders with finger-like invasions through the surrounding fat tissue together with a definitive thick-walled vascular pattern. In angio-myxomas, the intercellular matrix shows weak staining with Alcian blue while a dense positive staining is observed in ovarian myxomas due to the presence of hyaluronic acid ( 2 , 4 ).…”

“…For that reason, total excision of myxomatous ovarian tumors together with the adnexal structures was advised. Increases in mitotic activity, cellularity or nuclear atypia in tumors are the predictors that aid in an estimation of recurrences ( 2 ).…”