Myxomatous degeneration of mitral valve. M-mode and two dimensional echocardiographic findings.

Chun, Patrick K.C.; Sheehan, M W

doi:10.1136/hrt.47.4.404

Cited by 7 publications

(1 citation statement)

References 11 publications

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“…1982: myxomatous degeneration of mitral valve. Typical M-mode findings are shown, with mitral valve thickening and prolapse in the four-chamber view 82. 1984: echocardiographic and anatomical correlations in fetal congenital heart disease.…”

Section: Echocardiographymentioning

confidence: 94%

Let there be light! The meteoric rise of cardiac imaging

Reid

Dweck

2022

Heart

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Imaging plays a central role in modern cardiovascular practice. It is a field characterised by exciting technological advances that have shaped our understanding of pathology and led to major improvements in patient diagnosis and care. The UK has played a key international role in the development of this subspecialty and is the current home to many of the leading global centres in multimodality cardiovascular imaging. In this short review, we will outline some of the key contributions of the British Cardiovascular Society and its members to this rapidly evolving field and look at how this relationship may continue to shape future cardiovascular practice.

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Section: Echocardiographymentioning

confidence: 94%

Let there be light! The meteoric rise of cardiac imaging

Reid

Dweck

2022

Heart

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Association of Mitral Valve Prolapse and Systemic Abnormalities of Connective Tissue

Glesby

Pyeritz²

1989

JAMA

164

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More than half of all patients evaluated in our clinic for the possible diagnosis of a heritable disorder of connective tissue could not be classified in the current nosology, yet they had considerable clinical evidence of a systemic defect of the extracellular matrix. As a group, these patients share many manifestations of the Marfan syndrome including long limbs, deformity of the thoracic cage, striae atrophicae, mitral valve prolapse, and mild dilatation of the aortic root. Clinical clustering did not emerge when patients were stratified by mitral valve prolapse or aortic dilatation. The clinical phenotype of patients with mitral valve prolapse constitutes a continuum, from Marfan syndrome at one extreme to isolated mitral valve prolapse due to myxomatous proliferation of the valve leaflets. In the absence of biochemical or DNA markers, discerning whether a patient with mitral valve prolapse and mild aortic root dilatation (in the absence of ectopia lentis or a family history) has Marfan syndrome, or another heritable disorder of connective tissue, will continue to be a clinical challenge. Until subclassification based on refined clinical, genetic, and laboratory investigations is possible, the patients we describe are best seen as having an "overlap" heritable connective-tissue disorder. We suggest the acronym "MASS phenotype" to emphasize involvement of the mitral valve, aorta, skeleton, and skin.

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