N,2-Dibromo-6-chloro-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide: an efficient and homogeneous catalyst for one-pot synthesis of 4H-pyran, pyranopyrazole and pyrazolo[1,2-b]phthalazine derivatives under aqueous media

Abstract

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Recent Advances in Green Synthesis of 3,3′‐Spirooxindoles via Isatin–based One–pot Multicomponent Cascade Reactions in Aqueous Medium

“…Khazaei reported an eco‐friendly one‐pot method for the synthesis of spiro‐oxindoles derivatives in aqueous medium catalyzed by N ,2‐Dibromo‐6‐chloro‐3,4‐dihydro‐2 H ‐benzo[ e ][1,2,4]thiadiazine‐7‐sulfonamide 1,1‐dioxide (DCDBTSD) (Scheme ). Spiro‐pyran‐oxindoles ( 60 , 61 ), as well as spiro‐pyrazoline‐oxindoles ( 62 ) were synthesized via this one‐pot multicomponent reaction at 80 °C in water.…”

Fast Efficient and General PASE Approach to Medicinally Relevant 4H,5H‐Pyrano‐[4,3‐b]pyran‐5‐one and 4,6‐Dihydro‐5H‐pyrano‐[3,2‐c]pyridine‐5‐one Scaffolds

“…M.p. 253 – 254 °C (: 253 – 254 °C). 1 H‐NMR (300 MHz, (D 6 )DMSO): 2.27 ( s , Me); 4.41 ( s , CH); 7.10 – 7.16 ( m , 4 arom.…”

Deep eutectic solvent an efficient reaction medium for the synthesis of chromeno pyrazolo and indazolo phthalazine derivatives

“…Chromeno pyrazolo and indazolo phthalazine derivatives constitute a bridgehead hydrazine as a group of nitrogen‐containing heterocyclic compounds, which possess a multiplicity of pharmacological properties including anti‐inflammatory, antimicrobial, antifungal, anticonvulsant, vasorelaxant, antitumor and cardiotonic activities . Due to the large biological activity of phthalazine compounds, number of methods have been reported such as ionic liquids, magnetic nanoparticles, solid supported catalysts, heteropolyacids, β‐cyclodextrin, microwave, sulfonic acid, alumina nanoparticles and p‐TSA …”