“…As our ongoing phytochemical and pharmacological research project on this plant [8,9,10,11,12], four new alkaloids and four new natural products, along with 15 known analogues, were obtained, and their structures and absolute configurations were determined by extensive spectroscopic data analysis, including one-dimensional and two-dimensional-NMR, HRESIMS, and IR, specific rotation data, and electronic circular dichroism (ECD) experiments. The known compounds ( 4 – 22 , Figure 1) were identified by comparison of their spectroscopic and optical rotation data with those in the reported literature as 4- p -hydroxyphenyl-2(1 H )-quinolinone ( 4 ) [13], 2-(1 H -indol-2-yl)-6-methoxy-4(3 H )-quinazolinone ( 5 ) [14], 2-(2-hydroxyphenyl)-4(3 H )-quinazolinone ( 6 ) [15], 2-(but-3-en-1-yl)-4(3 H )-quinazolinone ( 7 ) [16], 2-(1 H -indol-2-yl)-4(3 H )-quinolinone ( 8 ) [17], tryptanthrin ( 9 ) [18], 3-(2,4-dioxo-1,2- dihydroquinazolin-3(4 H )-yl)propanoic acid ( 10 ) [19], indiforine C ( 11 ) [3], 4-(2,4-dioxo-1,2- dihydroquinazolin-3(4 H )-yl)butanoic acid ( 12 ) [20], methyl 4-(2,4-dioxo-1,2-dihydroquinazolin- 3(4 H )-yl)butanoate ( 13 ) [21], 3-(2-hydroxyphenyl)-4(3 H )-quinazolinone ( 14 ) [22], 3-(2-carboxyphenyl)-4(3 H )-quinazolinone ( 15 ) [23], 4-methyl-1,2-dihydro-2-oxoquinazoline ( 16 ) [24], 2-methyl-4(3 H )-quinazolinone ( 17 ) [25], 4-hydroxy-3-methyl-2(1 H )-quinolinone ( 18 ) [26], 2-amino-4-quinolinecarboxylic acid ( 19 ) [27], 4(1 H )-quinolinone ( 20 ) [28], 4(1 H )-quinolone-3- carboxylic acid ( 21 ) [29], and 1,2,3,4-tetrahydro-4-hydroxy-quinolinecarboxylic acid ( 22 ) [30]. The NO inhibitory activities of the isolates ( 1 – 23 ) were also evaluated against the LPS-stimulated RAW264.7 macrophages.…”