N-Isopropylacrylamide Copolymers with Acrylamide and Methacrylamide Derivatives of Cholic Acid: Synthesis and Characterization

Liu, Huiyou; Avoce, Damien; Song, Zhengji; Zhu, X. X.

doi:10.1002/1521-3927(20010601)22:9<675::aid-marc675>3.0.co;2-c

Cited by 55 publications

(44 citation statements)

References 11 publications

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“…Cholic acid was coupled to a (meth)acryloyl group via a spacer. 34,35 The obtained monomers were copolymerized with different N-alkyl acrylamides, with or without a cross-linker (structure III, Figure 4). Polymers with the structure IIIa were designed as imprinting materials.…”

Section: Polymerization Of Monomers Containing Bile Acidsmentioning

confidence: 99%

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Polymeric Materials Containing Bile Acids

2002

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Bile acids are biological compounds in the body that have interesting properties and have been used to make special chemical structures in molecular recognition. Various polymers have been synthesized from bile acids. The materials should preserve some of the properties of bile acids, such as biocompatibility, high stability of the steroid nucleus, reactivity of the side groups, optical activity and self-assembling capacity. The synthesis and applications proposed for such polymers are discussed.

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Section: Polymerization Of Monomers Containing Bile Acidsmentioning

confidence: 99%

“…Their LCST values decreased with increasing content of bile acid-bearing monomers. 35 Polycondensation of Bile Acids. The first attempt to perform bile acid polycondensation was reported by Ahlheim and Hallensleben, 36 who used p-toluenesulfonic acid as a catalyst and high reaction temperatures.…”

Section: Polymerization Of Monomers Containing Bile Acidsmentioning

confidence: 99%

Polymeric Materials Containing Bile Acids

2002

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“…Syntheses of compounds 1b-4b and 1b 0 -4b 0 Compounds 1b-4b and 1b 0 -4b 0 were prepared according to the literature procedure [22] with minor modification. Compounds 1a-4a or 1a 0 -4a 0 were dissolved in appropriate ethylenediamine or 1,6-hexanediamine and stirred at 73°C for 16 h. The reaction solution was quenched with ice-water and extracted three times with trichloromethane.…”

Section: 22mentioning

confidence: 89%

Synthesis and characterization of organometallic rhenium(І) and technetium(І) bile acid complexes

Huang

Zhu

et al. 2009

Journal of Organometallic Chemistry

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“…Indeed, in our group, we have prepared and modified various acrylamide-based block copolymers with CAs as pendant chains to study their effect on the tuning of the LCST. [45][46][47][48][49] Bile acids have the property of associating with ␤-cyclodextrin (␤-CD), due to the compatibility of the size and shape of bile acids with the cavity of ␤-CD. [50][51][52][53][54][55] This reversible association allows the tuning of the thermoresponsive properties via the addition of a supramolecular host.…”

Section: Thermoresponsive Polymers and Hydrogelsmentioning

confidence: 99%

Polymers made of bile acids: from soft to hard biomaterials

Cunningham

Zhu

2016

Can. J. Chem.

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Bile acids are gaining increasing importance as building blocks in the development of novel polymeric materials. This is evidenced by the growing number of publications advocating the advantages of their incorporation in the design and construction of materials. Composed of a rigid steroid backbone, functional groups with potential towards diverse reactions, and a biocompatible framework, there are various ways in which these molecules can be utilized to afford biomaterials via distinct architectures. Soft materials utilize the intrinsic capacity of bile acids to self-assemble and have seen a range of applications, most notably in the field of drug delivery. On the other hand, there is also the possibility of including bile acids in the polymer backbone, which has been used in the preparation of elastomers. This review discusses a selection of materials that can be prepared using bile acids and the advantages afforded by these molecules. Focus will be on the development of soft and hard materials, where soft materials are described as being held by weak intermolecular interactions, whereas hard materials are mechanically stronger with bile acids covalently incorporated in the polymer network.Key words: bile acids, polymers, biomaterials, drug delivery, dental composites. Résumé :Les acides biliaires sont des synthons de plus en plus importants dans la mise au point de nouveaux matériaux à base de polymères, comme en témoigne le nombre croissant de publications préconisant leur incorporation dans la conception et la fabrication de ces matériaux. Composées d'un squelette stéroïdien rigide, de groupes fonctionnels au potentiel réactionnel diversifié, et d'une structure biocompatible, ces molécules, de par leurs différentes architectures, présentent diverses possibilités d'application dans le domaine des biomatériaux. La capacité intrinsèque des acides biliaires à s'autoassembler permet de produire des matériaux souples dont les applications sont variées, notamment dans le domaine de la libération des médica-ments. Par ailleurs, la possibilité d'intégrer des acides biliaires dans le squelette de polymères a aussi été explorée dans le cadre de la fabrication d'élastomères. Le présent article de synthèse porte sur une sélection de matériaux pouvant être préparés à partir d'acides biliaires et sur les avantages que comportent ces molécules. Une attention particulière est accordée à la mise au point de matériaux souples et de matériaux rigides. On y décrit les matériaux souples comme étant maintenus par des interactions intermoléculaires faibles, tandis que les matériaux rigides, dans lesquels les acides biliaires sont incorporés dans le réseau polymérique par des liaisons covalentes, sont mécaniquement plus solides. [Traduit par la Rédaction]

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N-Isopropylacrylamide Copolymers with Acrylamide and Methacrylamide Derivatives of Cholic Acid: Synthesis and Characterization

Cited by 55 publications

References 11 publications

Polymeric Materials Containing Bile Acids

Polymeric Materials Containing Bile Acids

Synthesis and characterization of organometallic rhenium(І) and technetium(І) bile acid complexes

Polymers made of bile acids: from soft to hard biomaterials

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