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Abstract

This research emphasis on microwave assisted extraction of fruits of Sapindus mukorrosai. Aqueous fruit extract is subjected for the isolation of saponins, focusing only on higher molecular weight of saponins using dialysis membrane. On treatment of aqueous solution of silver nitrate with isolated saponin, stable silver nanoparticles were rapidly formed. The green synthesized silver nanoparticles were characterized by UV-vis spectroscopy, scanning electron microscope (SEM), energy dispersive X-ray (EDX). The SEM confirms the synthesis of square shape of nanocrystalline particles with the size range of 60-90 nm. The presence of saponins has confirmed by FTIR spectra. These nanoparticle has been subjected for hypolipidaemic activity in animal model. It showed significant reduction in total cholesterol, triglyceride level, HDL and VLDL parameters.