Nail dystrophies

Bodman, Myron

doi:10.1016/j.cpm.2004.05.005

Cited by 25 publications

(15 citation statements)

References 27 publications

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“…[ 4 ] Systemic diseases like Kawasaki disease, scarlet fever, hand-foot and mouth disease, thrombocytopenia and systemic lupus erythematosus have been reported to produce onychomadesis. [ 5 6 ] Various drugs implicated in the causation include antineoplastics and valproate. [ 7 ] Onychomadesis can also be idiopathic or familial.…”

Section: Discussionmentioning

confidence: 99%

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Onychomadesis with lichen planus: An under-recognized manifestation

Grover

Vohra

2015

Indian J Dermatol

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Onychomadesis or proximal separation of the nail pate usually results from severe, generalized dermatoses like bullous diseases, hand foot and mouth disease, varicella or severe cutaneous drug reactions. Although lichen planus (LP) produces varied nail manifestations (longitudinal onychorrhexis, onychoschizia, nail pigmentation, pterygium etc.), to the best of our knowledge, onychomadesis as a manifestation of nail LP is not recorded. This report presents two children with onychomadesis arising with generalized eruptive LP.

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Section: Discussionmentioning

confidence: 99%

“…[ 7 ] Onychomadesis can also be idiopathic or familial. [ 6 ] Nail involvement reportedly occurs in 10% of patients with LP with fingernails being more frequently affected. [ 8 ] It is more common in adults, and usually several nails are affected.…”

Section: Discussionmentioning

confidence: 99%

Onychomadesis with lichen planus: An under-recognized manifestation

Grover

Vohra

2015

Indian J Dermatol

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“…Ridging can develop in patients with psoriasis and lichen planus, and upon trauma or aging. 14 Our vitiligo patients were more frequently affected than the general podiatric populations. However, the pathogenesis remains unclear; thus, further study is needed.…”

Section: Discussionmentioning

confidence: 80%

Nail abnormalities in patients with vitiligo

Topal

Güngör

Kocatürk

et al. 2016

An. Bras. Dermatol.

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BackgroundVitiligo is an acquired pigmentary skin disorder affecting 0.1-4% of the general population. The nails may be affected in patients with an autoimmune disease such as psoriasis, and in those with alopecia areata. It has been suggested that nail abnormalities should be apparent in vitiligo patients.ObjectiveWe sought to document the frequency and clinical presentation of nail abnormalities in vitiligo patients compared to healthy volunteers. We also examined the correlations between nail abnormalities and various clinical parameters.MethodsThis study included 100 vitiligo patients and 100 healthy subjects. Full medical histories were collected from the subjects, who underwent thorough general and nail examinations. All nail changes were noted. In the event of clinical suspicion of a fungal infection, additional mycological investigations were performed.ResultsNail abnormalities were more prevalent in the patients (78%) than in the controls (55%) (p=0.001). Longitudinal ridging was the most common finding (42%), followed by (in descending order): leukonychia, an absent lunula, onycholysis, nail bed pallor, onychomycosis, splinter hemorrhage and nail plate thinning. The frequency of longitudinal ridging was significantly higher in patients than in controls (p<0.001).ConclusionsNail abnormalities were more prevalent in vitiligo patients than in controls. Systematic examination of the nails in such patients is useful because nail abnormalities are frequent. However, the causes of such abnormalities require further study. Longitudinal ridging and leukonychia were the most common abnormalities observed in this study.

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“…This seems thus to be periodic rather than continuous in time. The occasional appearance of the so-called Beau's lines (e.g., [10][11][12]) is also interpreted as clinical evidence of discontinuous nail growth. Beau's lines are associated with traumatic and/or pathological, rather than healthy nail circumstances, but their appearance provides further evidence of the nail ability to grow in a discontinuous manner.…”

Section: Basic Modelling Postulates and Considerationsmentioning

confidence: 99%

Small Strain Growth and the Human Nail

Soldatos

2015

J Elast

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is specialised to describe growth processes in which mass-growth may take place elastically at infinitesimally small strain. Growth-strain is considered infinitesimally small but the resulting simplified constitutive equations are in general still non-linear due to combined action of the rate of massgrowth and the rate of volumetric strain. Nevertheless, mass-growth processes which are either incompressible or slightly/moderately compressible are found consistent with linearly elastic material behaviour, and can accordingly be studied with convenient use of linear elasticity concepts. In a relevant example application, combination of the concept of periodically accumulated small strain with a certain nail-elongation criterion enables development of a relatively simple mathematical model of the human nail apparatus and, hence, an interesting interpretation of the nail elongation process. The efficiency of the model is demonstrated through a relevant analytical solution obtained in the particular case that mass-growth in the living part of the nail takes place under constant mass density and is, therefore, incompressible. Consideration of more advanced nail features and physical concepts can be handled in a similar manner, at the expense of parts of the pursued and desirable analytical simplicity.

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Nail dystrophies

Cited by 25 publications

References 27 publications

Onychomadesis with lichen planus: An under-recognized manifestation

Onychomadesis with lichen planus: An under-recognized manifestation

Nail abnormalities in patients with vitiligo

Small Strain Growth and the Human Nail

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