2016
DOI: 10.1111/vaa.12343
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Nalbuphine and butorphanol reverse opioid-induced respiratory depression but increase arousal in etorphine-immobilized goats (Capra hircus)

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Cited by 14 publications
(9 citation statements)
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“…Also, multiple butorphanol doses were required in the thiafentanil-medetomidine immobilised impalas to completely resolve apnoea. Similar to findings reported in etorphine-immobilised goats (Haw, Meyer & Fuller 2016 ), butorphanol, at the doses used, did not induce arousal from immobilisation but caused muscle relaxation in the goats and improved their breathing rate and rhythm.…”
Section: Discussionsupporting
confidence: 86%
“…Also, multiple butorphanol doses were required in the thiafentanil-medetomidine immobilised impalas to completely resolve apnoea. Similar to findings reported in etorphine-immobilised goats (Haw, Meyer & Fuller 2016 ), butorphanol, at the doses used, did not induce arousal from immobilisation but caused muscle relaxation in the goats and improved their breathing rate and rhythm.…”
Section: Discussionsupporting
confidence: 86%
“…Previous studies have demonstrated that effective and comprehensive postoperative analgesia does not only reduce postoperative pain in patients, but can also reduce the incidence of postoperative complications ( 3 ). The administration of nalbuphine, which does not affect circulatory function or increase the cardiac load ( 4 , 5 ), is commonly used for patients with hypertension and cardiac dysfunction ( 6 , 7 ). In the present study, we report the use of nalbuphine in the postoperative analgesic treatment of older patients with lower limb fractures after open reduction and internal fixation.…”
Section: Introductionmentioning
confidence: 99%
“…Naborphine, as a new type of synthetic opioid, has emerged its clinical value in recent years. Nalbuphine is a powerful analgesic showing low side effects and low dependence in animals and humans, and it has been shown to be effective against the respiratory inhibitory without attenuation of analgesia ( Klepper et al, 1986 ; Narver, 2015 ; Haw et al, 2016 ). Previous studies have confirmed that combination of dexmedetomidine and sufentanil on spinal anesthesia ( Karimi et al, 2021 ) or nalbuphine combined with dexmedetomidine in the postoperative treatment of laparoscopic oophorocystectomy ( Liu et al, 2021 ) achieved good clinical effects such as longer postoperative analgesia, reduced use of analgesic, and slight hemodynamic changes.…”
Section: Discussionmentioning
confidence: 99%