Nano‐ and Microencapsulation of Phytochemicals

Lee, Sung Je; Wong, Marie

doi:10.1002/9781118292327.ch6

Cited by 20 publications

(8 citation statements)

References 216 publications

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“…Although low‐energy methods such as spontaneous emulsification (SE), phase inversion temperature (PIT), phase inversion composition (PIC), and emulsion inversion point (EIP) methods may lower the degradation impact of sensitive bioactive compounds; however, their usage in food applications have been limited due to only nonionic small molecule surfactants (synthetic surfactants) can be used in these approaches. Natural biopolymers, including protein and polysaccharide emulsifiers, are unable to form nanoemulsions using low‐energy methods (Lee & Wong, ).…”

Section: Introductionmentioning

confidence: 99%

Effect of Emulsification Method and Particle Size on the Rate of in vivo Oral Bioavailability of Kenaf (Hibiscus cannabinus L.) Seed Oil

Cheong

Tan

Nyam

2018

Journal of Food Science

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Kenaf (Hibiscus cannabinus L.) seed oil-in-water nanoemulsions stabilized by complexation of beta-cyclodextrin with sodium caseinate and Tween 20 have been shown to have higher bioaccessibility of vitamin E and total phenolic content than nonemulsified kenaf seed oil in the previous in vitro gastrointestinal digestion study. However, its oral bioavailability was unknown. Therefore, the aim of this study was to evaluate the rate of in vivo oral bioavailability of kenaf seed oil-in-water nanoemulsions in comparison with nonemulsified kenaf seed oil and kenaf seed oil macroemulsions during the 180 min of gastrointestinal digestion. Kenaf seed oil macroemulsions were produced by using conventional method. Kenaf seed oil-in-water nanoemulsions had shown improvement in the rate of absorption. At 180 min of digestion time, the total α-tocopherol bioavailability of kenaf seed oil nanoemulsions was increased by 1.7- and 1.4-fold, compared to kenaf seed oil and macroemulsion, respectively. Kenaf seed oil-in-water nanoemulsions were stable in considerably wide range of pH (>5 and <3), suggesting that it can be fortified into beverages within this pH range PRACTICAL APPLICATION: The production of kenaf seed oil-in-water nanoemulsions had provided a delivery system to encapsulate the kenaf seed oil, as well as enhanced the bioaccessibility and bioavailability of kenaf seed oil. Therefore, kenaf seed oil-in-water nanoemulsions exhibit a great potential application in nutraceutical fields.

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Section: Introductionmentioning

confidence: 99%

Effect of Emulsification Method and Particle Size on the Rate of in vivo Oral Bioavailability of Kenaf (Hibiscus cannabinus L.) Seed Oil

Cheong

Tan

Nyam

2018

Journal of Food Science

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“…These preparations are made through the addition and mixing of lipophilic guest molecules into a cyclodextrin aqueous solution. This process, known as molecular inclusion complexation, results in the incorporation of hydrophobic molecules inside the ring structure of cyclodextrins [68]. b-Cyclodextrins (b-CD) are a family of cyclic oligosaccharides composed of a-(1-4) linked 6-,7-or 8-D-glucose units known to accommodate hydrophobic molecules and to form water-soluble inclusion complexes [63].…”

Section: Xanthophyll Formulations Not Yet Studied For Xanthophyll Stamentioning

confidence: 99%

Purification and Formulation of Xanthophyll for Pharmaceutical Use: Current Strategies and Future Trends

2015

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The increasing attention to biological activities of dietary xanthophylls demands the establishment of attractive and easy-to-implement purification protocols for their recovery from different sources. Bioengineering strategies that involve alternative isolation and purification techniques have gained interest since they offer practical benefits in comparison to traditional column chromatography methods. Furthermore, the use of these techniques has resulted in compound purities from 50 to 98 %. Besides purification, it is important to keep in mind that xanthophyll bioavailability is limited due to their low solubility in digestive fluids. Therefore, there is also the need to enhance xanthophyll bioavailability through formulations of the purified compounds. Several formulation techniques have been employed to obtain products for bioavailability or stability studies. However, there is a lack of studies that address the effect of the formulation upon the bioavailability and stability of these compounds. In the present review, emerging purification and formulation technologies that have shown potential for xanthophyll isolation and bioavailability enhancement are critically discussed. This analysis is presented in order to discuss the current trends in the purification and formulation technologies of xanthophylls, particularly for pharmaceutical use.

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“…Organic solvents are rarely used due to The attributes of spray-dried powders are associated with the operating conditions including feed flow rate, concentration of core and coating agent, speed of atomizer, drying air flow rate, and drying temperature [ 245 ]. Generally, polysaccharides (e.g., gum Arabic, maltodextrin, cyclodextrin with varying dextrose equivalent (DE)), and proteins (e.g., whey protein, milk protein, soy protein, and caseinate salts) are used for spray drying [ 246 ]. Nogueira et al [ 225 ] demonstrated good retention of antioxidant properties of spray-dried microcapsules of blackberry pulp (coating material arrowroot starch/gum Arabic: 1:1.78).…”

Section: Bulk Encapsulation Of Bioactive Compoundsmentioning

confidence: 99%

Innovative Technologies for Extraction and Microencapsulation of Bioactives from Plant-Based Food Waste and Their Applications in Functional Food Development

Pattnaik

Pandey

Martin

et al. 2021

Foods

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The by-products generated from the processing of fruits and vegetables (F&V) largely are underutilized and discarded as organic waste. These organic wastes that include seeds, pulp, skin, rinds, etc., are potential sources of bioactive compounds that have health imparting benefits. The recovery of bioactive compounds from agro-waste by recycling them to generate functional food products is of increasing interest. However, the sensitivity of these compounds to external factors restricts their utility and bioavailability. In this regard, the current review analyses various emerging technologies for the extraction of bioactives from organic wastes. The review mainly aims to discuss the basic principle of extraction for extraction techniques viz. supercritical fluid extraction, subcritical water extraction, ultrasonic-assisted extraction, microwave-assisted extraction, and pulsed electric field extraction. It provides insights into the strengths of microencapsulation techniques adopted for protecting sensitive compounds. Additionally, it outlines the possible functional food products that could be developed by utilizing components of agricultural by-products. The valorization of wastes can be an effective driver for accomplishing food security goals.

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Nano‐ and Microencapsulation of Phytochemicals

Cited by 20 publications

References 216 publications

Effect of Emulsification Method and Particle Size on the Rate of in vivo Oral Bioavailability of Kenaf (Hibiscus cannabinus L.) Seed Oil

Effect of Emulsification Method and Particle Size on the Rate of in vivo Oral Bioavailability of Kenaf (Hibiscus cannabinus L.) Seed Oil

Purification and Formulation of Xanthophyll for Pharmaceutical Use: Current Strategies and Future Trends

Innovative Technologies for Extraction and Microencapsulation of Bioactives from Plant-Based Food Waste and Their Applications in Functional Food Development

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