Nano-CuFe2O4 as a magnetically separable and reusable catalyst for the synthesis of diaryl/aryl alkyl sulfides via cross-coupling process under ligand-free conditions

Abstract

An efficient protocol was developed for the CuFe(2)O(4) nanopowder-catalyzed aryl-sulfur bond formation between aryl halide and thiol/disulfide. A variety of aryl sulfides were synthesized in impressive yields with good chemoselectivity and functional group tolerance in the presence of a catalytic amount of CuFe(2)O(4), Cs(2)CO(3) as base, in nitrogen atmosphere, under ligand-free conditions, in DMSO as solvent at 100 °C. The catalyst is air-stable, inexpensive, magnetically separable and recyclable up to four cycles.

The Application of Copper/Iron Cocatalysis in Cross-Coupling Reactions

“…[ . [26] Both aryl/aliphatic iodides and aryl/aliphatic thiols exhibited good reactivity in these reactions and the resulting diaryl or aryl alkyl sulfides were obtained in yields ranging from 70% to 98%. In addition, as an alternative sulfide source, diphenyl disulfide was also used to gain similar results to those by phenyl thiols.…”

FeCl3/SiO2 NPs as a robust and efficient catalyst for the synthesis of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones

“…The ethanol was evaporated and the solid was recrystallized from ethanol to get pure product. The structures of the products were fully established on the basis of their 1 H NMR, 13 C NMR and FT-IR spectra. 4-chlorophenyl)-1,2-dihydro-4-((2-hydroxynaphthalen-1-yl)(4-nitrophenyl) 19 (s, 3H, CH3), 6.31 (s,1H, CH), 7.14 (m, 1H, ArH), 7.29 (s, 1H, NH), 7.33 (m, 3H, ArH), 7.46 (m, 1H, ArH) 4-bromophenyl)(2-hydroxynaphthalen-1-yl)methyl)-2-(4-chlorophenyl)-1,2-dihydro-5-methyl pyrazol-3-one (5d) …”

Nano Copper Ferrite Catalysed Improved Procedure for One-Pot Synthesis of Poly Substituted Pyridine Derivatives

“…Nano copper ferrite has earlier been used as magnetically separable catalyst for several organic synthetic reactions such as asymmetric hydrosilylation of ketones 24 , synthesis of diaryl or aryl alkyl sulfides via cross coupling process under ligand free conditions 25 , synthesis of substituted benzoxazoles via Ullmann-type coupling under ligand free conditions 26 , cross-coupling of aryl halides with diphenyl diselenide 27 , green one-pot three component synthesis of spirooxindoles 28 , multicomponent synthesis of 1,4-di substituted 1,2,3-triazoles in tap water 29 and synthesis 1,4 dihydro pyridines involving aromatic aldehyde, ethylacetoacetate and ammonium acetate 30 .…”