Nanoarchitectonics prepared by laser processing and their biomedicinal applications

Gherasim, Oana; Grumezescu, Valentina; Socol, G.; Ficai, Anton

doi:10.1016/b978-0-12-816200-2.00018-9

Cited by 2 publications

(1 citation statement)

References 142 publications

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“…To overcome the limitations of post-implantation systemic antibiotherapy, the surface modification of implantable devices with nanocoatings that exert local antimicrobial effects has emerged as an efficient strategy for preventing or limiting their opportunistic contamination and colonization as well as decreasing the severity of related infective complications. The laser-assisted processing of coatings represents an attractive and successful strategy for improving the surface of implantable devices [ 40 , 41 ]. Among the available methods, the matrix-assisted pulsed laser evaporation (MAPLE) technique has attracted tremendous interest in engineering antimicrobial coatings, being particularly well-suited for organic thin film deposition [ 42 , 43 , 44 ].…”

Section: Introductionmentioning

confidence: 99%

Silver/Graphene Oxide Nanostructured Coatings for Modulating the Microbial Susceptibility of Fixation Devices Used in Knee Surgery

Constantinescu,

Niculescu,

Hudiță

et al. 2023

IJMS

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Exploring silver-based and carbon-based nanomaterials’ excellent intrinsic antipathogenic effects represents an attractive alternative for fabricating anti-infective formulations. Using chemical synthesis protocols, stearate-conjugated silver (Ag@C18) nanoparticles and graphene oxide nanosheets (nGOs) were herein obtained and investigated in terms of composition and microstructure. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) characterizations revealed the formation of nanomaterials with desirable physical properties, while X-ray diffraction (XRD) analyses confirmed the high purity of synthesized nanomaterials. Further, laser-processed Ag@C18-nGO coatings were developed, optimized, and evaluated in terms of biological and microbiological outcomes. The highly biocompatible Ag@C18-nGO nanostructured coatings proved suitable candidates for the local modulation of biofilm-associated periprosthetic infections.

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Section: Introductionmentioning

confidence: 99%

Silver/Graphene Oxide Nanostructured Coatings for Modulating the Microbial Susceptibility of Fixation Devices Used in Knee Surgery

Constantinescu,

Niculescu,

Hudiță

et al. 2023

IJMS

Self Cite

View full text Add to dashboard Cite

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Inorganic Nanoparticles in Bone Healing Applications

et al. 2022

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Modern biomedicine aims to develop integrated solutions that use medical, biotechnological, materials science, and engineering concepts to create functional alternatives for the specific, selective, and accurate management of medical conditions. In the particular case of tissue engineering, designing a model that simulates all tissue qualities and fulfills all tissue requirements is a continuous challenge in the field of bone regeneration. The therapeutic protocols used for bone healing applications are limited by the hierarchical nature and extensive vascularization of osseous tissue, especially in large bone lesions. In this regard, nanotechnology paves the way for a new era in bone treatment, repair and regeneration, by enabling the fabrication of complex nanostructures that are similar to those found in the natural bone and which exhibit multifunctional bioactivity. This review aims to lay out the tremendous outcomes of using inorganic nanoparticles in bone healing applications, including bone repair and regeneration, and modern therapeutic strategies for bone-related pathologies.

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Nanoarchitectonics prepared by laser processing and their biomedicinal applications

Cited by 2 publications

References 142 publications

Silver/Graphene Oxide Nanostructured Coatings for Modulating the Microbial Susceptibility of Fixation Devices Used in Knee Surgery

Silver/Graphene Oxide Nanostructured Coatings for Modulating the Microbial Susceptibility of Fixation Devices Used in Knee Surgery

Inorganic Nanoparticles in Bone Healing Applications

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