Nanocellulose: Insight into Health and Medical Applications

Halib, Nadia; Ahmad, Ishak

doi:10.1007/978-3-319-48281-1_5-1

Cited by 2 publications

(1 citation statement)

References 83 publications

(97 reference statements)

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“…It is reported that nanocellulose-based systems demonstrated sustained release of the loaded drug, with great biomedical applications [ 31 ]. In addition, nanocellulose can be used in food packaging [ 10 ], tissue engineering [ 32 ], cosmetic additives, medical implants [ 33 ], paper industry [ 34 ], 3D printing [ 35 ], wastewater treatment [ 36 ], biocatalysts [ 37 ], bioenergy [ 38 ](Zhu et al., 2016), wood adhesives, lenses, fingerprint detection [ 30 ](Trache et al., 2020), and textile industries [ 39 ](Forsman et al., 2017).…”

Section: Introductionmentioning

confidence: 99%

Nanocellulose, a versatile platform: From the delivery of active molecules to tissue engineering applications

Patil

Patel

Dutta

et al. 2022

Bioactive Materials

110

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Nanocellulose, a biopolymer, has received wide attention from researchers owing to its superior physicochemical properties, such as high mechanical strength, low density, biodegradability, and biocompatibility. Nanocellulose can be extracted from wide range of sources, including plants, bacteria, and algae. Depending on the extraction process and dimensions (diameter and length), they are categorized into three main types: cellulose nanocrystals (CNCs), cellulose nanofibrils (CNFs), and bacterial nanocellulose (BNC). CNCs are a highly crystalline and needle-like structure, whereas CNFs have both amorphous and crystalline regions in their network. BNC is the purest form of nanocellulose. The nanocellulose properties can be tuned by chemical functionalization, which increases its applicability in biomedical applications. This review highlights the fabrication of different surface-modified nanocellulose to deliver active molecules, such as drugs, proteins, and plasmids. Nanocellulose-mediated delivery of active molecules is profoundly affected by its topographical structure and the interaction between the loaded molecules and nanocellulose. The applications of nanocellulose and its composites in tissue engineering have been discussed. Finally, the review is concluded with further opportunities and challenges in nanocellulose-mediated delivery of active molecules.

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