Nanochemistry - A Split between 18th Century and Modern Times

Heinzerling, Peter; Oetken, Matthias

doi:10.12691/wjce-6-1-1

Cited by 6 publications

(3 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gold nanoparticles (GNPs, used to denote any size or shape nanoparticles) are among the most widely studied nanomaterials. Since the primary report on gold colloids over 100 years ago by Faraday [1,2], extensive research has been performed on their configurations, properties, and applications. GNPs exhibit a myriad of unique physical, optical, biological and chemical features [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein

et al. 2021

View full text Add to dashboard Cite

Gold nanoparticles have the potential to be used in biomedical applications from diagnostics to drug delivery. However, interactions of gold nanoparticles with different biomolecules in the cellular environment result in the formation of a “protein corona”—a layer of protein formed around a nanoparticle, which induces changes in the properties of nanoparticles. In this work we developed methods to reproducibly synthesize spheroidal and star-shaped gold nanoparticles, and carried out a physico-chemical characterization of synthesized anionic gold nanospheroids and gold nanostars through transmission electron microscopy (TEM), dynamic light scattering (DLS), zeta potential (ZP), nanoparticles tracking analysis (NTA), ultraviolet-visible (UV–Vis) spectroscopy and estimates of surface-enhanced Raman spectroscopy (SERS) signal enhancement ability. We analyzed how they interact with proteins after pre-incubation with bovine serum albumin (BSA) via UV–Vis, DLS, ZP, NTA, SERS, cryogenic TEM (cryo-TEM) and circular dichroism (CD) spectroscopy. The tests demonstrated that the protein adsorption on the particles’ surfaces was different for spheroidal and star shaped particles. In our experiments, star shaped particles limited the protein corona formation at SERS “hot spots”. This benefits the small-molecule sensing of nanostars in biological media. This work adds more understanding about protein corona formation on gold nanoparticles of different shapes in biological media, and therefore guides design of particles for studies in vitro and in vivo.

show abstract

Section: Introductionmentioning

confidence: 99%

Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The second step involves a disproportionation reaction in which metallic gold (Au 0 ) and trivalent gold (Au 3+ ) are produced. The overall reaction is shown in Figure 5 [29][30][31][32].…”

Section: Synthesis Of Gold Nanoparticlementioning

confidence: 99%

Gold Nanoparticles: A Didactic Step-by-Step of the Synthesis Using the Turkevich Method, Mechanisms, and Characterizations

et al. 2023

View full text Add to dashboard Cite

In this study, gold nanoparticles (AuNPs) were synthesized using the Turkevich method. This article explains the didactic step-by-step synthesis, showing pictures of the entire process, including a well-explained mechanism and characterization study. Synthesis involves the reduction of NaAuCl4 using sodium citrate at high temperatures (approximately 90 °C). The two main mechanisms used to explain AuNPs synthesis via the Turkevich method are also discussed. The first mechanism considers that a nanowire intermediary and the other proposes that aggregate intermediates are not formed at any time during the synthesis. The materials (NaAuCl4 and AuNPs) were characterized using UV-Vis spectroscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray diffraction (XRD), and dynamic light scattering (DLS). The UV-Vis spectrum exhibits an absorption maximum at 521 nm because of the surface plasmon resonance (SPR) absorption band of the AuNPs. The SEM images of NaAuCl4 show crystals with cubic shapes, while the AuNPs have an average particle size of approximately 16–25 nm and particles that appear mainly spherical. To confirm the particle shapes, AFM was conducted, and it was possible to clearly observe individual spherical nanoparticles and their aggregates, and the average diameter of these AuNPs was approximately 12–19 nm. The XRD pattern of AuNPs showed four main characteristic peaks corresponding to the (111), (200), (220), and (311) planes, confirming the presence of cubic (FCC) gold. The DLS presented an average particle size of 3.3 ± 0.9 nm and a polydispersity index (PDI) of 0.574. AuNPs were synthesized using a simple and rapid method. The resulting spherical and ultra-small particles can be used in several applications.

show abstract

“…Michael Faraday in 1857, conveyed the Royal Society Bakerian Lecture in London with the title of "Test Relations of Gold (and different metals) to light". Michael was the 1st to sense that shading was due to the gold particles moment size [7].…”

Section: Gold Nanoparticles Gnpsmentioning

confidence: 99%

The Physical Properties and Applications of Gold Nanoparticles (Au NPs): Review

Al-Wardy¹,

Rahi²

2021

sjpas

View full text Add to dashboard Cite

Nanoparticles of gold that for years have been recognized are the concept of an increasingly rising reports number and of promising for electronic, optical, magnetic, biomedical and catalytic applications in century of 21st. Because of Nanoparticles of gold stability, an interest in such research is a reason for performing the current work. There are various types of AuNPs: Zero-dimensional AuNps: quantum dots, spherical nanoparticles. AuNPs as 1-dimensional: nanowires, nano-rods, nano-belts, nanotubes. AuNPs as 2-dimensional: nano-plates of gold, nano-shell and, AuNPs as 3 dimensional: nano tadpoles of gold, nano- dumbbells of gold (AuNDs), AuNPs being spread, for example, nano-dendrites of gold, nano-pods, and nano-stars. Au NPs, in the field of medicine are investigated for several applications include vectors of drug delivery, agents of contrast, and therapy of localized heat, biomarkers of ultra-sensitive and more. AuNPs are very attractive material for biosensor, chemosensory, genosensor and immunosensor production

show abstract

Nanochemistry - A Split between 18th Century and Modern Times

Cited by 6 publications

References 18 publications

Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein

Gold Nanostars with Reduced Fouling Facilitate Small Molecule Detection in the Presence of Protein

Gold Nanoparticles: A Didactic Step-by-Step of the Synthesis Using the Turkevich Method, Mechanisms, and Characterizations

The Physical Properties and Applications of Gold Nanoparticles (Au NPs): Review

Contact Info

Product

Resources

About