Herein,
we report the development of novel antibacterial nanosanitizers
involving nine different essential oils (EOs) and a food-grade triblock
copolymer with polyethylene glycol and polypropylene glycol building
blocks that demonstrate unique, versatile release profiles. Furthermore,
this work also deals with the assessment and comparison of their inhibitory
properties against food pathogens in conjunction with their release
kinetics. The hydrodynamic diameter of EO nanosanitizers prepared
by flash nanoimbibition method ranged from 27.4 ± 0.5 to 41.4
± 0.1 nm. For these systems, three composite release kinetics
trends were discovered: (i) a release rate having an exponential association
behavior with time initially, which is followed by a linear decrease
for basil, cinnamon cassia, and star anise EOs; (ii) a release rate
having an exponential association behavior with time initially, which
is followed by a plateau for citronella and clove bud EOs; and (iii)
a release rate with a slow exponential association behavior with time
for clove leaf, eucalyptus, peppermint, and tea tree EOs. For a given
concentration, compared to bulk EOs, nanoimbibed EOs exhibited higher
inhibitory effects against Listeria monocytogenes and Escherichia coli O157:H7. The
order of antibacterial efficacy for bulk EOs was cinnamon cassia >
peppermint ∼ clove leaf > clove bud > citronella >
eucalyptus
∼ tea tree > star anise. On the contrary, the order of antibacterial
potency for EO nanosanitizers was clove bud ∼ clove leaf ∼
cinnamon cassia > star anise ∼ citronella ∼ peppermint
> tea tree > eucalyptus. These differences indicate that, aside
from
the chemistry of EO, the nanostructural details of their assembly
and local distribution of EO constituents play a role in inhibiting
bacterial growth.