Nanomaterials for Chronic Kidney Disease Detection

Abstract

Chronic kidney disease (CKD) is a dilapidating problem that causes great global burden since the current therapeutic options are mostly ineffective. Early diagnosis and efficient treatment are essential to prevent the progression of CKD. Nanoparticles as technological drivers of innovation have emerged in biomedical studies for different theranostic applications. Several nanoparticles have been developed, which can be labeled with targeting moieties for both drug delivery and/or imaging systems and are investigated to detect different pathological conditions. The focus of this review is to demonstrate the current research and clinical applications for nanoparticles in the diagnosis of CKD and other renal diseases that will probably result in CKD.

Electric field-directed migration of mesenchymal stem cells enhances their therapeutic potential on cisplatin-induced acute nephrotoxicity in rats

“…Recent studies proved that MSC-derived nanovesicles are novel in treating renal failure (Eftekhari et al 2021 ). Moreover, Maleki Dizaj et al ( 2021 ) explored the potential use of various nanoparticles, such as carbon nanotubes and nanofibrous membranes, to treat kidney disorders as well as to detect and monitor chronic renal failure early on using a variety of diagnostic techniques.…”

“…For instance, using of various nanomaterials (e.g., carbon nanotubes and nanofibrous membranes), MSC-derived nanovesicles, and nanomaterial-based adsorbents and membranes in wearable blood purification systems and synthetic kidneys as novel emergent techniques in treating renal failure (Eftekhari et al 2021 ). Moreover, Maleki Dizaj et al ( 2021 ) discussed the potential role of nanoparticles not only in treating kidney diseases but also in early detection and monitoring of chronic renal failure via different diagnostic applications, e.g., nanoparticle enhanced immunosensors for serum kidney biomarkers, in addition to nanoparticle enhanced renal imaging techniques.…”

A novel online calculator based on clinical features and hematological parameters to predict total skin clearance in patients with moderate to severe psoriasis

“…Identifying patients who are more likely to respond to IL-17 inhibitors has significant clinical implications. It enables personalized treatment decisions, ensuring optimal therapy selection and potentially reducing treatment failures, healthcare costs, and improving patient outcomes [ 11 , 12 ]. In this study, we will develop a nomogram based on the logistic regression model to provide a visual representation of the predictive factors and their corresponding probabilities of achieving TSC.…”

Production of value-added cosmetic products from cold-pressed Helianthus annuus L. oil and pulp

“…This keeps rising consumption from outpacing population density and upsetting the natural equilibrium, therefore protecting the environment. Saving a significant amount of energy is also made possible by recycling recyclable resources as raw materials (Khalilov & Nasibova, 2010;Dizaj et al, 2021).…”