Nanomaterials for electrochemical non-enzymatic glucose biosensors

Abstract

This review overviews the recent development of nanomaterials for the application of electrochemical non-enzymatic glucose biosensors. The electrocatalytic mechanism and glucose sensing performance of a variety of nanostructured materials including metallic nanoparticles, metal oxides, metal complexes, alloys and carbon nanomaterials are discussed. The merits and shortfalls of each nanomaterial as electrocatalyst for non-enzymatic biosensing are evaluated and the prospects of non-enzymatic glucose biosensors are presented.

Effect of Urea on the Morphology of Co3O4 Nanostructures and Their Application for Potentiometric Glucose Biosensor

“…up to 21 days. Therefore we can infer that the electrodes cannot be stable after this period and that can be attributed to; in one hand, could be assigned to a well suited network and good compatibility of nano-flowers of Co3O4 for GOx at the time of immobilization [24] and on the other hand, the short-term stability of enzymatic glucose biosensor is probably due to the thermal and chemical instability of GOx [25]. Table 2 shows comparative data for the glucose determinations using different electrodes immobilized and non-immobilized GOx.…”

Copper/nickel nanoparticle decorated carbon nanotubes for nonenzymatic glucose biosensor

“…Owning to their excellent electrocatalytic properties, high chemical stability, high conductivity, and extremely high mechanical strength, CNTs have found substantial applications in the electrode modification, leading to enhanced surface roughness, porosity, and biocompatibility [30,31]. Although pristine CNTs are directly responsive to glucose and unaffected by the interfering species, a major limitation lies in the narrow linear range in glucose determination [32,33]. Therefore, CNTs are frequently used in conjunction with other catalytically active metals and alloys as well as metal oxides [2,8,18,25].…”

NiS Hollow Spheres for High‐Performance Supercapacitors and Non‐Enzymatic Glucose Sensors

“…Up to date, many nano/microstructured materials have been successfully used for the construction of non-enzymatic glucose sensors, such as Ni, Cu, and CuS materials. [39][40][41][42] However, to the best of our knowledge, there are few reports on the fabrication of non-enzymatic glucose detectors based on NiS micro/nanomaterials. Until now, despite the success in the preparation of NiS hollow structures, the synthesis of hollow structures of NiS by a simple route still remains as a significant challenge.…”