2020
DOI: 10.3389/fnano.2020.610465
|View full text |Cite
|
Sign up to set email alerts
|

Nanomedicine & Nanotoxicology Future Could Be Reshaped Post-COVID-19 Pandemic

Abstract: Since its first emergence in December 2019, the coronavirus-2 infection has quickly spread around the world and the severity of the pandemic has already re-shaped our lives. This review highlights the role of nanotechnology in the fight against this pandemic with a focus on the design of effective nano-based prevention and treatment options that overcome the limitations associated with conventional vaccines and other therapies. How nanotechnology could be utilized to understand the pathology of the ongoing pan… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
10
0

Year Published

2021
2021
2023
2023

Publication Types

Select...
5
2
1
1

Relationship

0
9

Authors

Journals

citations
Cited by 13 publications
(10 citation statements)
references
References 92 publications
(94 reference statements)
0
10
0
Order By: Relevance
“…Dexamethasone nanomedicine that is used previously for treatment of rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis was proposed to administer for COVID-19 patients [ 84 ]. Lipid nanoparticles as delivering particles (NLPs) were used by Imperial College London and Arcturus Therapeutics to design and develop encapsulated self-replicating mRNA vaccines [ 85 ]. Zhang et al [ 86 ] developed cellular nanosponges using plasma membrane of pulmonary type II epithelia cells or human macrophages.…”
Section: Treatmentmentioning
confidence: 99%
“…Dexamethasone nanomedicine that is used previously for treatment of rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis was proposed to administer for COVID-19 patients [ 84 ]. Lipid nanoparticles as delivering particles (NLPs) were used by Imperial College London and Arcturus Therapeutics to design and develop encapsulated self-replicating mRNA vaccines [ 85 ]. Zhang et al [ 86 ] developed cellular nanosponges using plasma membrane of pulmonary type II epithelia cells or human macrophages.…”
Section: Treatmentmentioning
confidence: 99%
“…The chemical nature of the lipids used permits them to overcome their endosomal sequestration in the cell, as shown for cationic DOTAP/DOPC fusogenic liposomes [ 8 , 9 ]. They are efficiently used as cargos to deliver drugs into cells [ 10 , 11 ] and extracellular vesicles [ 12 , 13 ]. Recently, efforts have been focused to rationalize the mechanism of the interaction between the lipidic bilayers and nanoparticles (NPs), such as magnetic maghemite nanoparticles, quantum dots [ 14 ], or hydrophobic gold nanoparticles [ 15 , 16 , 17 , 18 ], depending on the fluidity of the lipidic membrane [ 19 ] and the NP size [ 20 ].…”
Section: Introductionmentioning
confidence: 99%
“…NDDS is a system used for delivery of a drug to the targeted site other than conventional drug delivery systems for the betterment of patient [2]. NDDS have various advantages over conventional systems such as optimum dosing at the right time and right location, efficient use of expensive drugs, reduction in production cost, beneficial to patients, and improved comfort and standard of living [3].In December 2019, the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) was discovered, which then precipitated the emergence of the largest global pandemic [4]. These viruses mutate regularly and COVID-19 has undergone thousands of mutations since it first emerged.…”
Section: Introductionmentioning
confidence: 99%