“…Membrane separation process is one of the most effective techniques to solve the water issues and has been widely deployed in various fields such as chemical engineering, food engineering and pharmaceutical industry as well. − Up to now, the most membranes were prepared using polymeric materials such as polyamide (PA), polyvinylidene fluoride (PVDF), poly(ether sulfone) (PES), and cellulose acetate fiber (CA), whose features include easy processing, low cost, and excellent separation. − Nevertheless, because of their poor biodegradability, waste membranes always cause secondary environmental problems, which are increasingly taken into account and researched. − Ceramic materials were believed as an alternative that was easily regenerated at a high temperature. However, the high cost of ceramic materials hampers the wide application of ceramic membranes. , Most recently, biodegradable polymers have attracted lots of attention since they could be degradable with certain specific microorganisms or proteins while quite stable under service conditions. − PLA is such a kind of biodegradable polymeric materials that has been widely deployed in a wide range of medical applications. ,− Because PLA contains plenty of hydrophobic functional groups such as methyl groups and ester groups, it shows strong hydrophobic property . This always leads to serious fouling when applied as separation membranes. , Several attempts have gone into reducing the hydrophobicity of PLA nanofiber membranes and the membrane fouling through tailoring the surface roughness, − for example, introducing hydrophilic functional groups by incorporating TiO 2 nanoparticles.…”