2018
DOI: 10.1155/2018/6231482
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Nanoparticles in Medicine: A Focus on Vascular Oxidative Stress

Abstract: Nanotechnology has had a significant impact on medicine in recent years, its application being referred to as nanomedicine. Nanoparticles have certain properties with biomedical applications; however, in some situations, they have demonstrated cell toxicity, which has caused concern surrounding their clinical use. In this review, we focus on two aspects: first, we summarize the types of nanoparticles according to their chemical composition and the general characteristics of their use in medicine, and second, w… Show more

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Cited by 156 publications
(93 citation statements)
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References 190 publications
(198 reference statements)
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“…Practicability of any nanosized polymer particles as a drug carrier relies on its efficacy to encapsulate the drug and its sustained release behavior. To test this, we used SNP, a NO donor, which is used as a drug for hypertension, vascular, and obstructive diseases, and analyzed the loading and release capacity of pLME. The extent of drug loading capacity of nanocapsules was estimated by UV–Vis spectroscopy using 0.0666 M solution of drug, as mentioned in materials and methods section.…”
Section: Resultsmentioning
confidence: 99%
“…Practicability of any nanosized polymer particles as a drug carrier relies on its efficacy to encapsulate the drug and its sustained release behavior. To test this, we used SNP, a NO donor, which is used as a drug for hypertension, vascular, and obstructive diseases, and analyzed the loading and release capacity of pLME. The extent of drug loading capacity of nanocapsules was estimated by UV–Vis spectroscopy using 0.0666 M solution of drug, as mentioned in materials and methods section.…”
Section: Resultsmentioning
confidence: 99%
“…Nanoparticles, materials that are from 1 to 100 nanometers (nm) in size, have been used for synthesis of metal nanostructures, nanofibers, nanotubes, nanorods, nanofluids, semiconductors, quantum dots, nanoalloys, and magnetic crystals (Aziz et al, 2015;Prasad et al, 2016;Singhal et al, 2017), sustainable agriculture , in dermatological topical applications (Antonio et al, 2014), medicine (Mauricio et al, 2018), and also, more recently, in microbiome interventions, with a particular focus directed toward for cancer treatment and blockade therapy (Karavolos and Holban, 2016;Song et al, 2019). Many metals are used in nanomedicines -for example, silver nanoparticles are used as antimicrobials.…”
Section: Potential For Nanotechnologymentioning
confidence: 99%
“…Ceramics and quantum dots are used as drug vehicles, bioimaging and biosensors. Fullerene and carbon nanotubes are suitable as imaging agents [67].…”
Section: Nanobio-interface and Its Role In Cellular Behaviormentioning
confidence: 99%