Nanoparticles-induced inflammatory cytokines in human plasma concentration manner: an ignored factor at the nanobio-interface

Tirtaatmadja, Nicolin; Mortimer, Gysell M.; Ng, Eng-Poh; Ahmad, Haçan Ali; Mintova, Svetlana; Serpooshan, Vahid; Minchin, Rodney F.

doi:10.1007/s13738-014-0486-7

Cited by 13 publications

(8 citation statements)

References 20 publications

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“…Neutralizing the charge by surface modification of the nanosystem with other polymers or materials prevents binding of protein corona to the nanosystem and then activation of the immune response. Tirtatmadja et al observed that a variation of the protein corona composition at the nanosystem affected the production of IL-8 and TNF-α inflammatory cytokines [ 280 ]. Benita et al demonstrated that cationic group-coated PNs activated the immune response (inflammation) more than anionic group-coated PNs.…”

Section: Pharmacokinetics Biodistribution and Nanotoxicologymentioning

confidence: 99%

Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections

2020

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Polymeric nanocarriers (PNs) have demonstrated to be a promising alternative to treat intracellular infections. They have outstanding performance in delivering antimicrobials intracellularly to reach an adequate dose level and improve their therapeutic efficacy. PNs offer opportunities for preventing unwanted drug interactions and degradation before reaching the target cell of tissue and thus decreasing the development of resistance in microorganisms. The use of PNs has the potential to reduce the dose and adverse side effects, providing better efficiency and effectiveness of therapeutic regimens, especially in drugs having high toxicity, low solubility in the physiological environment and low bioavailability. This review provides an overview of nanoparticles made of different polymeric precursors and the main methodologies to nanofabricate platforms of tuned physicochemical and morphological properties and surface chemistry for controlled release of antimicrobials in the target. It highlights the versatility of these nanosystems and their challenges and opportunities to deliver antimicrobial drugs to treat intracellular infections and mentions nanotoxicology aspects and future outlooks.

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Section: Pharmacokinetics Biodistribution and Nanotoxicologymentioning

confidence: 99%

Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections

2020

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“…Another unconsidered challenge in BMC studies is the inconsistency of the experimental environment and analysis methods employed in the related published articles. [ 114–116 ] For example, plasma concentration, [ 117,118 ] temperature, [ 96,119 ] incubation time, [ 96 ] pH, [ 96 ] type of separation method (e.g., in gel or on‐particle), [ 115 ] type of informatics database, and statistical analysis methods [ 115 ] are some of the parameters that differ widely in the published literature. To minimize these inconsistencies, Lynch and coworkers have suggested a guideline entitled “Minimum Information about Nanomaterial Biocorona Experiments (MINBE)” to enhance interoperability, reproducibility, and utility of BMC characterizations.…”

Section: The Challenges and Prospects Of Biomolecular Corona Consideration In Carbon‐based Nanomaterials Biodegradation Studiesmentioning

confidence: 99%

Biodegradation of Carbon‐Based Nanomaterials: The Importance of “Biomolecular Corona” Consideration

Mokhtari‐Farsani

Hasany

Lynch

et al. 2021

Adv Funct Materials

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It has been over a decade since oxidative enzymes were first used to degrade carbon‐based nanomaterials (CBNs). Although enormous progress has been achieved in this field, many questions and problems remain unresolved that need to be answered to usher these materials toward their true destiny. Nanobioscience researchers now know that ignoring the biomolecular corona (BMC) in nanobiomedical studies, either inadvertently or intentionally, is by no means justified. However, a major drawback to progress is that BMC effects on CBN biodegradation have been omitted from a large number of studies. What's more, many studies in the field have eliminated the BMC source in the relevant experiments. Thus, the most critical question that one needs to probe is whether the BMC and its characteristics affect the biodegradability of CBNs? In this conceptual perspective paper, recent progress and significant research in CBNs biodegradation are summarized. Then, the importance of the BMC and its possible impacts on the biodegradation of CBNs are thoroughly explored as a conceptual guide. Finally, remaining challenges and the direction of future research are provided, and barriers that need to be overcome to advance the field are discussed including recommendations regarding BMC considerations and study design and reporting guidelines.

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“…Thus the EMT nanosized zeolite can be considered as very promising material for purification of fibrinogen and lipoproteins, while keeping the highest concentration of albumin, when they are exposed to in vivo-like human plasma concentration. 181 Fibrinogen is a very complex, hydrophilic and bipolar molecule. In contrary to fibrinogen, apolipoprotein C-III (APOC-III) is a simple, highly hydrophobic and non-polar molecule.…”

Section: Biological and Medical Applications Of Nanosized Zeolitesmentioning

confidence: 99%

Nanosized microporous crystals: emerging applications

2015

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This review highlights recent developments in the synthesis and unconventional applications of nanosized microporous crystals including framework (zeolites) and layered (clays) type materials. Owing to their microporous nature nanosized zeolites and clays exhibit novel properties, different from those of bulk materials. The factors controlling the formation of nanosized microporous crystals are first revised. The most promising approaches from the viewpoint of large-scale production of nanosized zeolites and clays are discussed in depth. The preparation and advanced applications of nanosized zeolites and clays in free (suspension and powder forms) and fixed (films) forms are summarized. Further the review emphasises the non-conventional applications of new porous materials. A comprehensive analysis of the emerging applications of microporous nanosized crystals in the field of semiconductor industry, optical materials, chemical sensors, medicine, cosmetics, and food industry is presented. Finally, the future needs and perspectives of nanosized microporous materials (zeolites and clays) are addressed.

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Nanoparticles-induced inflammatory cytokines in human plasma concentration manner: an ignored factor at the nanobio-interface

Cited by 13 publications

References 20 publications

Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections

Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections

Biodegradation of Carbon‐Based Nanomaterials: The Importance of “Biomolecular Corona” Consideration

Nanosized microporous crystals: emerging applications

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