Nanopharmaceuticals and Nanocosmeceuticals

Nasir, Adnan

doi:10.1002/9781118384824.ch5

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…Nanostructured lipid carriers (NLC) are one of the delivery systems developed to increase the penetration of active compounds into the skin. 4-6 NLC is a lipid nanoparticle generally consisting of solid lipids, liquid lipids, and emulsifiers having a particle size distribution of up to 500 nm. 7 , 8 The type and ratio of lipids used in NLC affect the morphology and particle size, trapping effectiveness, system stability, and penetration of active compounds into the skin.…”

Section: Introductionmentioning

confidence: 99%

The effect of peppermint oil addition on the physical stability, irritability, and penetration of nanostructured lipid carrier coenzyme Q10

Erawati

Arifiani

Miatmoko

et al. 2023

J. Public Health Afr.

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Background: Coenzyme Q10 is formulated into Nanostructured Lipid Carrier (NLC) added with peppermint oil (PO) 0% (F1), 1% (F2), 1.5% (F3) and 2% (F4) to increase its penetration. Objective: This study aims to determine the effect of PO addition on the irritability, stability, and penetration of Coenzyme Q10 in the NLC. Methods: Coenzyme Q10 NLC was prepared using the High Shear Homogenization method. Furthermore, physical characterization was carried out. Physical stability testing was carried out for 90 days at a temperature of 25±5oC and an RH of 60±10%. The in vivo irritation test was observed for mice’s back skin after 24 hours while the penetration study was further evaluated at 2 hours of the sample application. Results: Increasing the PO amount into Coenzyme Q10 NLC reduced the viscosity which was 329.1±15.5 cps for PO 0% to 219.9±2.9 cps for 2% addition. The observation of particle morphology showed that all NLC Coenzyme Q10 has a spherical particle shape with particle size between 188.25±13.22 to 197.80±14.19 nm. All formulas had high entrapment efficiency (>80%). PO addition did not cause changes in physical characteristics during 90 days of storage. The 24 hours’ irritation test showed that F2 and F3 are non-irritating. By PO addition skin penetration improved at 2 hours’ penetration study. Conclusion: PO addition up to 2% reduced viscosity, but did not affect particle size and morphology of Coenzyme Q10 NLC. Addition of PO up to 1.5% increased entrapment efficiency, did not irritate and increased the penetration of Coenzyme Q10 NLC.

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Section: Introductionmentioning

confidence: 99%

The effect of peppermint oil addition on the physical stability, irritability, and penetration of nanostructured lipid carrier coenzyme Q10

Erawati

Arifiani

Miatmoko

et al. 2023

J. Public Health Afr.

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Emerging Trends of Nanomaterials in Cosmeceuticals

Gaikwad,

Dange,

Nayakal

et al. 2023

AJPR

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Cosmetic industry is booming in the beauty care market. New areas such as nanocosmetics and nanocosmeceuticals are emerging to grow this market. Cosmeceuticals are the cosmetic products which incorporates the biologically active ingredients which have therapeutic effects on the surface being applied. The primary goal of this review paper is to deliver a critical and comprehensive discussion on the role of nanomaterials in modern cosmetic science. This text includes an interpretation of the data underlying generic information reported on the product labels of formulations already available in the marketplace, information that often lacks details identifying specific components of the product, especially when nanomaterials are employed. It is not new news for cosmetic companies that nanotechnology is the way of the future and it is considered to be the most popular and developing technology available. For providing better and better UV protection, long lasting effects, deeper skin penetration, and increased colour and finish quality the cosmetic developers are using nanoscale versions of ingredients.

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Nanopharmaceuticals and Nanocosmeceuticals

Cited by 2 publications

References 25 publications

The effect of peppermint oil addition on the physical stability, irritability, and penetration of nanostructured lipid carrier coenzyme Q10

The effect of peppermint oil addition on the physical stability, irritability, and penetration of nanostructured lipid carrier coenzyme Q10

Emerging Trends of Nanomaterials in Cosmeceuticals

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