2023
DOI: 10.4081/jphia.2023.2515
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The effect of peppermint oil addition on the physical stability, irritability, and penetration of nanostructured lipid carrier coenzyme Q10

Abstract: Background: Coenzyme Q10 is formulated into Nanostructured Lipid Carrier (NLC) added with peppermint oil (PO) 0% (F1), 1% (F2), 1.5% (F3) and 2% (F4) to increase its penetration. Objective: This study aims to determine the effect of PO addition on the irritability, stability, and penetration of Coenzyme Q10 in the NLC. Methods: Coenzyme Q10 NLC was prepared using the High Shear Homogenization method. Furthermore, physical characterization was carried out. Physical stability testing was carried out for 90 days … Show more

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“…A sample weighing approximately 2 mL was placed on the middle plate and then elevated to a position directly below the cone. 14 The sample was located in the shear area between the stationary plate and the rotating cone. The velocity was adjusted via a dial selector, which either raised or lowered the shear speed.…”
Section: Viscosity Determinationmentioning
confidence: 99%
“…A sample weighing approximately 2 mL was placed on the middle plate and then elevated to a position directly below the cone. 14 The sample was located in the shear area between the stationary plate and the rotating cone. The velocity was adjusted via a dial selector, which either raised or lowered the shear speed.…”
Section: Viscosity Determinationmentioning
confidence: 99%