Nanorobotics System Simulation in 3D Workspaces with Low Reynolds Number

Abstract

Abstract:We present a computational approach to enable the development of nanorobots operating in a fluid environment relevant for medical applications. Unlike the case of larger robots, the dominant forces in this environment arise from viscosity of low Reynolds number fluid flow and Brownian motion and such parameters are described throughout the paper. Hence, this paper describes a practical simulator that allows fast design methodology comparing various control algorithms for nanorobots and their suitability for different tasks. The simulator includes obstacles and identifiable targets, thereby providing a suitable environment for a typical nanorobot task: maintaining desired chemical concentrations near specific target areas.

Nano Robots in Medicine: A Review

“…The atherosclerotic lesion was reduced due to Nano robot's activation. The parameters generated from the CFD simulation, namely velocities, temperature, signaling values, pro-inflammatory cytokines and soluble adhesion molecules concentrations, are transferred to the NCD [3,[5][6][7]36] simulator to be included into the Nano robots operating environment [45][46][47]. As the Nano robot should perform a pre-defined task in a specific target area, the trigger must be activated when the Nano robot is as close as possible to the target.…”

“…However, a decisive factor to determine the chances for a patient with cancer to survives: how earlier it was diagnosed; what means, if possible, a cancer should be detected at least before the metastasis has begun. Another important aspect to achieve a successful treatment for patients is the development of efficient targeted drug delivery to decrease the side effects from chemotherapy [35,38,[43][44][45][46][47]. Considering the properties of Nano robots to navigate as blood borne devices, they can help on such extremely important aspects of cancer therapy.…”

Dynamics of Carbon Nanotube Tipped Atomic Force Microscopy in Liquid

“…In a flow model with a low Reynolds number, inertial forces on the object are also small. By assuming the liquid is an incompressible liquid that satisfies Navier-Stokes continuum equations, the main force that is applied is the drag from the fluid (Cavalcanti et al, 2006).…”

Nanorobot Movement: Challenges and Biologically inspired solutions

“…Diffusion (random walk) due to thermal agitation (Brownian motion) appears to be an important mode of propulsion in the size range below 600 nm to move small objects in fluid at room temperature [21,[26][27]. Eukaryotic and Prokaryotic cells have different mechanisms to utilize diffusion and elasto-hydrodynamic interaction of rotating or beating cilia or flagella to move in nano-regimes [28][29][30][31][32][33]. All through literature, it is established that finite stiffness or non-rigidity of beating filament, for example in eukaryotic cells like mammalian sperms, is crucial in motion.…”