Nanotechnology-based siRNA delivery strategies for treatment of triple negative breast cancer

Recent Progress of RGD Modified Liposomes as Multistage Rocket Against Cancer

“…The least cell viability by RGD-PEG-BF-LIP was due to the tumor homing effect as RGD peptide was up taken by cancer cells having integrin receptor on the surface ( Zhang Y. et al, 2019 ). Due to the transformations in research, siRNA-based therapy ( Butt et al, 2016 ; Chadar et al, 2021 ) has also gained significant attention among scientists. Maximum therapeutic benefit could be achieved if such molecules could be made available at the desired site.…”

Clinical progress of therapeutics and vaccines: Rising hope against COVID-19 treatment

“…Viral vectors are genetically modified viral particles, which can produce SARS-CoV-2 proteins inside the host cells [124] , [125] , [126] , [127] , [128] , [129] , [130] , [131] , [132] . These viral vectors are non-pathogenic that carry the particular SARS-CoV-2 gene (mostly S-protein gene) to produce the protein in the host cells.…”

“…These nucleic acids induce the production of pathogen proteins in vivo , which stimulate the adaptive immune system. This platform is relatively new and currently, a few of these vaccines are licensed based on this technology [128] , [131] , [139] , [140] , [141] , [142] , [143] . This technology allows the rapid development of vaccines because millions of copies of protein-specific nucleic acids can be generated from a template using the polymerase chain reaction (PCR) technique.…”

Recent update on electrospinning and electrospun nanofibers: current trends and their applications

“…Nowadays a maximum number of drug targeting methods are based on nano-formulations because targeting therapy becomes easier when given in the form of a nano-formulation. [7][8][9][10][11][12][13][14][15][16] In the category of nano-formulations nanobers have vast application in the eld of medicines, [17][18][19][19][20][21][22][23][24][25] and amongst the nanobers the magnetic nanobers have different applications due to their characteristics and magnetic memory, as well as environmental treatment, catalysts, and biomedicine. 26,27 Nanobers can be simply dened as the bers of the polymers having the size in the range of nanometer where the temperature of calcination and holding time affects the shape, diameter, ber morphology, and crystallite size of the nanober structure.…”

“…Nowadays a maximum number of drug targeting methods are based on nano-formulations because targeting therapy becomes easier when given in the form of a nano-formulation. 7–16 In the category of nano-formulations nanofibers have vast application in the field of medicines, 17–19,19–25 and amongst the nanofibers the magnetic nanofibers have different applications due to their characteristics and magnetic memory, as well as environmental treatment, catalysts, and biomedicine. 26,27…”