Nanotechnology-Based Strategies for Treatment of Obesity, Cancer and Anti-microbial Resistance: Highlights of the Department of Science and Innovation/Mintek Nanotechnology Innovation Centre Biolabels Research Node at the University of the Western Cape

Abstract

Nanotechnology has recently received much interest in various fields, including medicine. South Africa (SA) was the first country in Africa to adopt the technology with the aim of enhancing the national bio-economy and global competitiveness by using innovative nanotechnology-based solutions. Since its inception in 2005 in SA, researchers have seized opportunities to increase and develop niche areas for its application in the health, energy, food, agriculture, and water sectors. We ventured into this field and have performed pioneering work on nanotechnology-based treatment strategies over the years. This perspective highlights the journey, with associated successes over the years, in order to display the impact of our nanotechnology research in health. The focus is on the nanotechnology outputs that have emanated from the Department of Science and Innovation (DSI)/Mintek Nanotechnology Innovation Centre (NIC) Biolabels Research Node (BRN) at the University of the Western Cape (UWC). BRN’s research interests were on nano-enabled materials for developing therapeutic agents, photothermal sensitizers, and targeted drug-delivery systems for treatment of chronic diseases and antimicrobial resistance.

Green Synthesis of Silver Nanoparticles Using Jacobaea maritima and the Evaluation of Their Antibacterial and Anticancer Activities

“…Nanotechnology significantly accelerates the advancement of medical innovations with several special features for overcoming 2 of 17 microbial antibiotic resistance [1]. Particularly, nanoparticles (NPs) possess remarkable properties, such as nano-size and charge, and exhibit significant anticancer and antimicrobial effects [3][4][5].…”