Naproxen’s Effect on Performance Within Neuromuscular Parameters

Abstract

This study investigated whether naproxen has an ergogenic effect on neuromuscular performance. A randomized, double-blind, placebo-controlled, crossover trial was conducted on 11 resistance-trained men who performed one strength-training session after taking 500 mg of naproxen and another session after taking a placebo. Participants performed three sets of the horizontal bench press with a load of 90% of repetition maximum (RM) to concentric failure. Outcome variables included number of repetitions, workload, fatigue index (FI), and delayed onset muscle soreness (DOMS). Results showed a statistically insignificant reduction in the number of repetitions for placebo when compared to naproxen, amounting to a relative difference of 44.89%. DOMS was lower in the naproxen group, but differences between conditions were not statistically significant. A statistically significant treatment effect was found for workload, favoring naproxen treatment. A statistically significant difference was found for FI between the second and third sets compared to the first set, with results favoring naproxen. We concluded that naproxen helps enhance neuromuscular outcomes in an acute high-intensity strength training bout.

Effect of ginger on the lower limb anaerobic power of brazilian national team gymnasts

“…In response to exercise, the synthesis of infl ammatory cytokines, such as TNF-α, is regulated by diff erent signaling pathways, including the COX-prostaglandin cascade 5 . Studies have analyzed the use of drugs by athletes in order to promote the inhibition of these infl ammatory processes 6,7,8 . Through their inhibitory eff ect on COX-1 and COX-2 enzymes, nonsteroideal antiinfl ammatory drugs (NSAIDs) have been shown to reduce infl ammatory responses that occur in the acute recovery phase of exercise 9 .…”