Nasal Nocardiosis in a Calf.

Abstract

ABSTRACT. Nasal nocardiosis was found in a female Japanese Black calf, 11 months of age. Macroscopically, the posterior half of the left nasal passage was completely obstructed by yellowish brown caseous substance and the mucosa was irregularly thickened. In the brain, a few soft brown foci were present in the olfactory bulb and frontal lobe. Microscopically, there were closely packed granulomas in the nasal cavity and brain. The lesions were characterized by a center of cellular debris surrounded by epithelioid macrophages, neutrophils, lymphocytes and multinucleated giant cells of the Langhans type. Special stains revealed the presence of a large number of filamentous branching gram-positive, partially acid-fast organisms in these epithelioid cells and giant cells, and in cellular debris.-KEY WORDS: calf, nasal cavity, nocardiosis.

Mycotic bovine nasal granuloma

“…While the nocardial nasal granuloma described by SHIBAHARA et al 11 in a Holstein heifer corresponded to a severe eosinophilic infiltration with multinucleated giant cells, the nasal nocardiosis published by TAKAHASHI et al 12 in a female Japanese Black calf appears to be well comparable in its histopathology to our first case.…”

Bovine nasal eosinophilic granuloma with blood eosinophilia caused by Nocardia species

“…1,2 The lesions are seen chiefly in the mammary glands in cattle, but a case of nasal nocardiosis has been reported in a calf. 3 In contrast, mycotic nasal granuloma, 4,5 characterised by eosinophilic granulomas containing fungal elements, is a disease of cows, and its histogenesis is distinct from ordinary pyogranulomas. Here we describe an unusual case of bovine nocardiosis, the most striking feature of which was infiltration of eosinophils.…”

Histological Study of Bovine Nocardial Eosinophilic Granuloma with Comparison of Splendore-Hoeppli Material

“…Nocardial sulfur granules are usually absent or inconspicuous (Husain 2012), but obvious in certain human cases (Rodig et al 2001, Shimizu et al 2001. Sulfur granules are absent, or at least have not been described in bovine nocardiosis with neutrophilic inflammation (Bawa et al 2010, Pisoni et al 2008, Saito et al 2009, Takahashi et al 1999.…”