Nasopharyngeal cylindrical cell papilloma

Abstract

Cylindrical cell papilloma is a possible cause of eustachian tube obstruction in adults. Effective treatment of these lesions usually requires wide endoscopic excision, in order not to miss coexistent carcinoma.

Schneiderian Papillomas: Comparative Review of Exophytic, Oncocytic, and Inverted Types

“…In contrast, mucoepidermoid carcinoma, epidermoid carcinoma, and sinonasal undifferentiated carcinomas have been seen with oncocytic papilloma. 8,9,16 The etiology of carcinoma development is controversial, with theories attributing malignant transformation to HPV-16 and -18. Some suggest that infection with HPV may occur early in the process of tumorigenesis with several other insults required to transform benign IP to dysplasia or malignancy.…”

“…10 Five to 15% of cases of IP can be associated with malignancy and 4–17% of cases of oncocytic papillomas have been associated with malignancy. 2,16,17 Malignant transformation can occur at the time of diagnosis or develop later at the site of previous resection. 9 In this series, all cases of dysplasia or malignancy were seen with IP, and of these, all were diagnosed at the initial resection.…”

“…1,23 Five to 60% of IP cases can recur, and 25–35% of OSP cases can recur within 5 years of resection. 8,9,16,17 Although much less common, recurrences can occur with exophytic papillomas in up to 22%. 2,10 Several factors have been shown to increase the risk of recurrence for IP including tobacco exposure, increased tumor size, increased hyperkeratosis, squamous epithelial hyperplasia, increased number of mitoses, bilaterality, and the lack of inflammatory polyps.…”

Primary tumors and tumor-like lesions of the eustachian tube: a systematic review of an emerging entity

“…They affected three males with a mean age of 55 (range 44-68) years. Four single cases of different benign ET pathology have been also included (online only Table 7) [76][77][78][79]. The entire spectrum of primary pathology of ET is summarized in the Tables (Tables 1, 2, 3, 4).…”

“…Single cases of primary osteoma [76], cartilaginous horn [77], and cylindrical cell papilloma [79] of ET have been reported. Granulomatous lesions can affect ET following surgical treatment of patulous ET resulting in hyatrogenic foreign body granuloma [78].…”