Natalia Sergeevna Andreeva 1922–2006

Wlodawer, Alexander

doi:10.1038/nsmb0107-2

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Crystals and Drug Discovery: The International Scene1

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2020

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“…For example, when I first visited Russia for the International Crystallography Meeting in 1966, Boris Vainshtein, who was Head of the Institute of Crystallography, was already strongly supporting the work on biological systems. At this time, Natalia Andreeva work on pepsin, the structure of which was eventually published in 1976 at high resolution [103,104].…”

Section: Crystals and Drug Discovery: The International Scenementioning

confidence: 99%

A Personal History of Using Crystals and Crystallography to Understand Biology and Advanced Drug Discovery

Blundell

2020

Crystals

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Over the past 60 years, the use of crystals to define structures of complexes using X-ray analysis has contributed to the discovery of new medicines in a very significant way. This has been in understanding not only small-molecule inhibitors of proteins, such as enzymes, but also protein or peptide hormones or growth factors that bind to cell surface receptors. Experimental structures from crystallography have also been exploited in software to allow prediction of structures of important targets based on knowledge of homologues. Crystals and crystallography continue to contribute to drug design and provide a successful example of academia–industry collaboration.

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Section: Crystals and Drug Discovery: The International Scenementioning

confidence: 99%

A Personal History of Using Crystals and Crystallography to Understand Biology and Advanced Drug Discovery

Blundell

2020

Crystals

View full text Add to dashboard Cite

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Natalia Sergeevna Andreeva 1922–2006

Cited by 1 publication

References 5 publications

A Personal History of Using Crystals and Crystallography to Understand Biology and Advanced Drug Discovery

A Personal History of Using Crystals and Crystallography to Understand Biology and Advanced Drug Discovery

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