National action towards a world free of cervical cancer for all women

Torode, Julie; Kithaka, Benda; Chowdhury, Raveena; Simelela, Nothemba; Cruz, Jennifer L.; Tsu, Vivien

doi:10.1016/j.ypmed.2020.106313

Cited by 12 publications

(6 citation statements)

References 41 publications

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“…Was das Ziel der Behandlungsmöglichkeiten diagnostizierter zervikaler Erkrankungen anbelangt, wurde 2019 in den Ländern mit hohem Durchschnittseinkommen die angesteuerte Zahl von 90 % bereits erreicht, während die Niedriglohnländer mit < 15 % weit unter der angestrebten Zielwert liegen [ 22 ], was die Notwendigkeit der gerechten weltweiten Verteilung der Impfstoffe unterstreicht [ 15 ].…”

Section: Impfziel: Eliminierung Des Zervixkarzinomsunclassified

14 Jahre HPV-Impfung: was haben wir erreicht?

Wojcinski

2021

Gynäkologe

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Professor Harald zur Hausen, „Vater der HPV(humane Papillomviren)-Impfung“, wurde in diesem Jahr 85 Jahre alt. Aus diesem Anlass wird in einem Rückblick auf die Einführung der HPV-Impfung vor 14 Jahren geschaut, und es werden die Widerstände aufgezeigt, welche die ersten Jahre dieser segensreichen Impfung begleiteten. Schon früh wurde 2007 die Impfung für die Mädchen in das Standardimpfprogramm der Ständigen Impfkommission am Robert Koch-Institut (STIKO) aufgenommen, erst 11 Jahre später kam es zur Empfehlung auch für Jungen. Die Impfquoten in beiden Gruppen sind mit ca. 50 % in Deutschland weiterhin im Vergleich zu anderen Ländern mit Schulimpfprogrammen zu niedrig. Dabei gibt es keine wissenschaftlichen Bedenken mehr gegenüber der HPV-Impfung, die sich in weltweiten Studien als sicher und wirksam erwiesen hat. Nicht nur die Verminderung der Krebsvorstufen, sondern auch von Zervixkarzinomen konnte neben der starken Reduktion von Fällen an Condylomata acuminata bei den Geimpften inzwischen in Real-Life-Studien gezeigt werden, weshalb die WHO (World Health Organization) als Impfziel die Eliminierung des Zervixkrebses durch Aufbau einer Bevölkerungsimmunität erklärt hat. Dazu sollten weitere Anstrengungen unternommen werden, die Impfquoten in Deutschland zu erhöhen, was auch in einem entsprechenden Appell der Gesundheitsministerkonferenz im Juni 2021 eingeflossen ist.

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Section: Impfziel: Eliminierung Des Zervixkarzinomsunclassified

14 Jahre HPV-Impfung: was haben wir erreicht?

Wojcinski

2021

Gynäkologe

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“…There is also evidence linking HPV with cancers of the anus, vulva, vagina, penis, and oropharynx (1,3). HPV risk increases with persistence and development of cervical cancer, HPV type-its oncogenicity or cancer-causing strength; immune status-people who are immune-compromised, such as those living with HIV (5); co-infection with other sexually transmitted agents (3), such as herpes simplex, chlamydia, and gonorrhea; and tobacco smoking (2,5).…”

Section: Introductionmentioning

confidence: 99%

“…Comprehensive cervical cancer control includes primary prevention (vaccination against HPV), secondary prevention (screening and treatment of pre-cancerous lesions), tertiary prevention (diagnosis and treatment of invasive cervical cancer), and palliative care (3,5). Vaccines that protect against HPV 16 and 18 are recommended by the World Health Organization (WHO) and have been approved for use in many countries (3).…”

Section: Introductionmentioning

confidence: 99%

Knowledge, willingness to support, and reasons for not supporting wives for cervical cancer screening in rural Dire Dawa administration, eastern Ethiopia: A qualitative study

Mohammed

Legesse

2023

Preprint

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Background: Husbands’ support is an important factor in spouses’ decisions to utilize reproductive health care services, including screening. Despite this, it is still poorly understood in the study area. Therefore, this study was aimed at exploring it, and this may help to fill the gap via interventions related to screening. Methodology: A community-based phenomenological qualitative study was undertaken in the rural Dire Dawa administration, Ethiopia, from September 1 to October 30, 2022. Data was collected from purposively selected husbands via in-depth interviews using a semi-structured tool aided by a voice recorder and field notes. A thematic analysis done with an inductive approach goes through six steps: familiarization, coding, generating themes, reviewing themes, defining and naming themes, and writing up. Results: Thematically, three main themes and sixteen sub-themes were identified, and in general, one-third of the husbands had knowledge of cervical cancer; however, aside from signs and symptoms, they lacked knowledge of the cause, risk factors, transmission, complications, cervical cancer treatment, screening, and other prevention methods. They each have different perceived reasons for not supporting their wives' screening. Conclusion: Husbands lack knowledge of cervical cancer and their perceptions of the disease and screening are negative, and this is explored as being a major barrier to supporting wives’ cervical cancer screening. Therefore, it is recommended that information regarding cervical cancer and screening be disseminated not only to women but also to men, as well as conducting additional community-based research.

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“…Cervix cancer is a central problem and a severe threat to women's lives. 1 According to Ferlay et al, cancer of the cervix takes the fourth position in cancer globally among females, predicting new cases of 570 000 women in 2018. 2 The most significant number of patients is detected in the low-and middle-income countries (LMICs), with over 85% of Sub-Saharan Africa (SSA) having the most significant problem universally.…”

Section: Introductionmentioning

confidence: 99%

The Prevalence of Human Papillomavirus in Women Living with HIV in Mukono General Hospital, Uganda

Nantale,

Nyagero,

Kemigisha

2023

Epidemiol Health System J

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Background and aims: High-risk oncogenic genotype human papillomavirus (HPV) infection induces cervical cancer (CaCx), a common cancer in women globally. Women living with human immunodeficiency virus (WLHIV) have a greater risk of hr-HPV infection and perseverance, enhancing the risk of defects in the cells of the cervix and aggressive CaCx. However, its prevalence in WLHIV is not apparent. The main objective of this research was to explore the types and prevalence of HPV infection by genotyping HPV among a cohort of WLHIV attending an antiretroviral therapy (ART) clinic in Mukono, Uganda. Methods: A cross-sectional study was conducted among women aged 25 to 49 years attending an ART clinic in a public health facility in Mukono, Uganda. Systematic random sampling was used to select 342 WLHIV from a target population of 3000. Only participants who had an Xpert HPV test between July 2021 and December 2022 were selected and interviewed, and their responses were analyzed using descriptive statistics. Results: Slightly more than half (56.7%) of the participants were under 35 years old, married (52.6%), and with a primary level of education (51.2%). The prevalence of hr-HPV was 39.8% (95% CI: 34.40-44.78). Of the total participants, 136 (39.8%) were high-risk HPV positive, with HPV 16, HPV18/45, and other hr-HPV types (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) being positive in 23 (6.7%), 21 (6.1%), and 110 (32.2%), respectively, while 17 (12.5%) had mixed hr-HPV infections. Conclusion: There is a high prevalence of HPV infection among WLHIV, underscoring the need to frequently screen and diagnose CaCx pre-cancerous lesions for its effective prevention.

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National action towards a world free of cervical cancer for all women

Cited by 12 publications

References 41 publications

14 Jahre HPV-Impfung: was haben wir erreicht?

14 Jahre HPV-Impfung: was haben wir erreicht?

Knowledge, willingness to support, and reasons for not supporting wives for cervical cancer screening in rural Dire Dawa administration, eastern Ethiopia: A qualitative study

The Prevalence of Human Papillomavirus in Women Living with HIV in Mukono General Hospital, Uganda

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