National Cancer Control Program of Thailand

Insamran, Weerawut; Sangrajrang, Suleeporn

doi:10.31557/apjcp.2020.21.3.577

Cited by 35 publications

(28 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Considering the alarming rates of disease also reported elsewhere in the country, the Cameroonian Government should make mammography, the current gold standard for breast cancer screening, available for free to rural populations, for instance, through screening campaigns. BSE, a low-cost screening option which proved to be effective in similar contexts [1,33], could be examined and recommended to women during these campaigns as it is the case in various successful breast cancer screening programs worldwide [14,17,22,34]. Surprisingly, 79 (16.63%) participants refused clinical examination in this study, as they feared discovering breast cancer or to show their breasts to the medical professionals performing the examinations due to religious reasons (to preserve their intimacy).…”

Section: Discussionmentioning

confidence: 87%

“…This explains why, in most African countries like Cameroon, breast cancer survival rate is low. Thus, breast cancer screening among population should be a priority in this country, particularly in rural areas where healthcare centers are lacking [21][22][23], considering that breast cancer incidence is expected to be different as compared to cities due to environmental differences [24][25][26].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Awareness of Breast Cancer Screening among the Medical and General Population of the North Region of Cameroon

Tagne

Baiguerel

Kamdje

et al. 2021

International Journal of Breast Cancer

View full text Add to dashboard Cite

Breast cancer has become a real public health problem in Cameroon, particularly in rural areas due to late diagnosis, resulting partly from the absence of national screening programs. This work is aimed at assessing breast cancer awareness in the North Region of Cameroon. Participants were selected in six health centers surrounding the rural area of Garoua, North Region, Cameroon, and administered a questionnaire aimed at assessing their awareness about breast cancer risk factors and screening. Out of the 475 women (including 37 medical personnel) interviewed, 45.5% attended at least secondary school; 91.3% were aware of the disease with the main sources of information from those around them (64.8%), media (46.5%), and health professionals in health facilities (42.7%). 23.3% had misconceptions and myth-based ideas on the origin of the disease. Ignorance was the main reason preventing the performance of breast self-examination, and the high cost prevents individuals from going for mammography. The highest awareness rate was observed in employed women with higher level of education. Our study highlights the need to raise awareness among the populations in North Region, Cameroon, about the risk factors and clinical signs of breast cancer and the importance of screening practice for early diagnosis of breast cancer.

show abstract

Section: Discussionmentioning

confidence: 87%

Section: Introductionmentioning

confidence: 99%

Awareness of Breast Cancer Screening among the Medical and General Population of the North Region of Cameroon

Tagne

Baiguerel

Kamdje

et al. 2021

International Journal of Breast Cancer

View full text Add to dashboard Cite

show abstract

“…Cancer is a leading cause of death worldwide [ 1 , 2 ]. According to the GLOBOCAN report, an estimated 19.3 million new cancer cases occurred in 2020, and of this number, oral cancer accounts for 377,713 cases and 177,757 deaths [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer

et al. 2022

View full text Add to dashboard Cite

Many types of cancer have metabolic alterations with increased glycolysis. Identification of alternative sweeteners that do not fuel cancer is a novel approach to cancer control. The present study aimed to investigate the effects of xylitol on tumor growth and survival of mice bearing orthotopic xenograft of tongue cancers. The results showed that partial substitution of glucose with xylitol (glucose 0.35 g plus xylitol 2.06 g/kg body weight) non-significantly reduced tumor volume, and significantly prolonged the median survival time from 19 days in the control to 30.5 days in the xylitol group. Immunohistochemical data of the tongue tissue shows significantly lower intense-to-mild staining ratios of the proliferation marker Ki-67 in the xylitol than those of the control group (p = 0.04). Furthermore, the xylitol substitution significantly reduced the expression of the rate-limiting glycolytic enzyme, phosphofructokinase-1 (PFK-1) (p = 0.03), and showed a non-significant inhibition of PFK activity. In summary, partial substitution of glucose with xylitol at the equivalent dose to human household use of 10 g/day slows down tumor proliferation and prolongs survival of mice bearing an orthotopic oral cancer xenograft, possibly through glycolytic inhibition, with minimal adverse events. The insight warrants clinical studies to confirm xylitol as a candidate sweetener in food products for cancer survivors.

show abstract

“…Up-to-date data are needed for policy makers, especially when CCA could also be the result from other causes despite O. viverrini infection. 40,41 MATERIALS AND METHODS Stool preparation. According to the screening program, the Office of Public Health in each district performed the Kato-Katz stool examination for Opisthorchis-like egg detection.…”

Section: Introductionmentioning

confidence: 99%

Genetic Differentiation of Opisthorchis-Like Eggs in Northern Thailand Using Stool Specimens Under National Strategic Plan to Control Liver Fluke Infection and Cholangiocarcinoma

Buathong

Phaiphilai²,

Ruang-areerate

et al. 2020

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Liver fluke infection caused by Opisthorchis viverrini is recognized as a potential risk factor for cholangiocarcinoma (CCA). The National Strategic Plan to Control Liver Fluke Infection and Cholangiocarcinoma has implemented microscopic-based stool examination screening. However, eggs of O. viverrini and minute intestinal flukes (MIFs) are nearly morphologically similar and could result in inaccurate O. viverrini diagnosis. Stool specimens were collected from eight districts of Chiang Mai Province in northern Thailand. Opisthorchis-like eggs were identified with the Kato-Katz technique and differentiated for O. viverrini and MIFs using molecular study by PCR and PCR-restriction fragment length polymorphism targeting the internal transcribed spacer 2 (ITS2) gene. Prevalence of Opisthorchis-like eggs was 5.9% from a total of 9,570 specimens. From PCR assays, all liver flukes were O. viverrini and all MIFs were Haplorchis taichui. The distribution of species was H. taichui (38.2%), O. viverrini (10.5%), coinfection of H. taichui and O. viverrini (37.2%), and 14.1% were negative from PCR. Totally, H. taichui was found in 75.4% of infections from Opisthorchis-like specimens. ITS2 nucleotide sequencing analysis showed a single variant of O. viverrini with no variation and two variants of H. taichui. This study first revealed the genetic background of Opisthorchis-like eggs in northern Thailand. Minute intestinal flukes are occasionally misdiagnosed as O. viverrini leading to misinterpretation and overestimation of the burden of O. viverrini infection. Molecular diagnosis such as PCR could effectively discriminate species of Opisthorchis-like eggs and help shape the robustness of epidemiological data to control liver fluke infection and raise awareness of other risk factors for CCA.

show abstract

National Cancer Control Program of Thailand

Cited by 35 publications

References 12 publications

Awareness of Breast Cancer Screening among the Medical and General Population of the North Region of Cameroon

Awareness of Breast Cancer Screening among the Medical and General Population of the North Region of Cameroon

Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer

Genetic Differentiation of Opisthorchis-Like Eggs in Northern Thailand Using Stool Specimens Under National Strategic Plan to Control Liver Fluke Infection and Cholangiocarcinoma

Contact Info

Product

Resources

About