National Clinical Recommendations for Obesity: Concept and Prospects

Недогода, С. В.; Barykina, I. N.; Salasyuk, A. S.

doi:10.19163/1994-9480-2017-1(61)-134-140

Cited by 14 publications

(6 citation statements)

References 4 publications

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“…Анализировали состав тела методом биоэлектрического импеданса на мониторе Omron BF-508 с оценкой процентного содержания в организме подкожного и висцерального жира. Под висцеральным ожирением подразумевали содержание висцерального жира в организме ≥9% [12]. Степень выраженности дисфункции жировой ткани изучали путем расчета индекса висцерального ожирения (VAI) [13].…”

Section: материалы и методыunclassified

The effect of non-alcoholic fatty liver disease on the functional state of the kidneys in patients with chronic heart failure

Стаценко

Туркина

Fabritskaya

et al. 2021

jour

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Aim: to study the functional state of the kidneys in patients with chronic heart failure (CHF) and non-alcoholic fatty liver disease (NAFLD).Materials and methods. 144 patients with CHF aged 45-70 years were divided into two groups: group 1 — persons with CHF and NAFLD, group 2 — CHF without NAFLD. A clinical examination was performed, the indices of FLI steatosis and NFS liver fibrosis were calculated, the functional state of the kidneys and the adipokine status were evaluated.Results. The main group of patients with CHF and NAFLD is mainly represented by people with grade I obesity (73 (84%) vs 5 (9%), p<0.05). Among patients with CHF and NAFLD, a clinically significant decrease in GFR<60 ml/min/1.73 m2 was significantly more often detected compared to patients with CHF without NAFLD (37% vs 21% in groups 1 and 2, respectively). The level of albuminuria was significantly higher in the group of patients with CHF and NAFLD (200.7±22.3 [54.7;390] vs 92.6±23.4 [10.2;188.7] mg/g in groups 1 and 2, respectively). The percentage of individuals with an AU/CR. urine ratio >30 mg/g was statistically significantly higher in group 1 compared to group 2 (82.1 vs 51.1% in groups 1 and 2, respectively). The level of serum leptin was significantly higher and the concentration of serum adiponectin was significantly lower compared to group 2 in the main group of patients with CHF and NAFLD compared to the control group. There was a significantly higher occurrence of insulin resistance in patients with CHF and NAFLD. Correlation analysis revealed the presence of statistically significant associations between the parameters characterizing the functional state of the kidneys and the indices of FLI, NFD, adipokines, and the severity of insulin resistance.Conclusion. In patients with CHF and NAFLD, a significant deterioration in the functional state of the kidneys was found, in comparison with patients with “isolated” CHF with comparable FC.

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Section: материалы и методыunclassified

The effect of non-alcoholic fatty liver disease on the functional state of the kidneys in patients with chronic heart failure

Стаценко

Туркина

Fabritskaya

et al. 2021

jour

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“…Общие рекомендации по изменению образа жизни [2,[4][5][6][7][8][9][10]20] Наиболее действенный способ профилактики и лечения ожирения заключается в рациональном питании с учетом индивидуальных нарушений здоровья и соблюдением трех основных принципов: умеренности, разнообразия и режима приема пищи [2,4,20]. Еда должна обладать приятными органолептическими свойствами, хорошо усваиваться, быть разнообразной, безопасной в отношении микроорганизмов, токсических веществ и радионуклидов.…”

Section: принципы и подходы к лечению ожиренияunclassified

“…При недостаточной эффективности рационального питания и физических нагрузок применяется медикаментозная терапия [2,[6][7][8].…”

Section: гастроэнтерология/Gastroenterologyunclassified

“…Кроме того, частое развитие тяжелых сопутствующих заболеваний у лиц с ожирением сопровождается повышением инвалидизации и смертности [2,3,6,7]. Показано, что продолжительность жизни пациентов с ожирением в среднем сокращается на 12-15 лет, а смертность в 12 раз выше, чем среди сверстников с нормальной массой тела [5,6].…”

Section: Introductionunclassified

“…Показано, что продолжительность жизни пациентов с ожирением в среднем сокращается на 12-15 лет, а смертность в 12 раз выше, чем среди сверстников с нормальной массой тела [5,6]. К заболеваниям, ассоциированным с ожирением, относятся прежде всего артериальная гипертензия, дислипидемия, атеросклероз, ишемическая болезнь сердца, сахарный диабет (СД) 2 типа [2,3,[5][6][7]. Ожирение также является фактором риска развития патологии желудочно-кишечного тракта (неалкогольная жировая болезнь печени, желчнокаменная болезнь, холестероз желчного пузыря, панкреатит) и опорно-двигательного аппарата (остеоартроз, подагра) [8][9][10][11].…”

Section: Introductionunclassified

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Modern methods to follow-up of obese patient

Ахмедов¹,

Gudim²

2020

Russian Medical Inquiry

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Obesity and its concomitant diseases preserve to be an urgent problem of modern medicine, as they are widespread worldwide and lead to negative medical, social and economic consequences that damage both patients and the state. The article presents statistical data reflecting the situation of obesity in Russia, describes the risk factors of obesity, highlights modern methods to follow-up of patients with obesity (e.g., correction of lifestyle and nutrition with the calorie control, change in physical activity, the use of pharmacological drugs and conducting various types of bariatric interventions). It is noted that the key factors that prevent the obesity development and control the body weight are rational nutrition (taking into account individual health problem), compliance with the principles of moderation, diversity, and dietary intake. Besides, it may be useful to practice wellness techniques (e.g., callanetics), which help to reduce and normalize body weight and develop concentration and stress tolerance. Special attention is paid to the obesity effect on the course of COVID-19 infection, which causes higher susceptibility and the development of severe complications. KEYWORDS: obesity, overweight, risk factor, rational nutrition, diet, physical activity. FOR CITATION: Akhmedov V.A., Gudim A.S. Modern methods to follow-up of obese patient. Russian Medical Inquiry. 2020;4(5):308–313. DOI: 10.32364/2587-6821-2020-4-5-308-313.

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The state of the main arteries, vascular age in patients with arterial hypertension and obesity: the role of leptin and adiponectin

Стаценко

Деревянченко

2019

Russ J Cardiol

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Aim.To study the state of the main arteries and vascular age in conjunction with the level of leptin and adiponectin in patients with arterial hypertension (AH) and obesity.Material and methods. One hundred and twenty patients with AH stage II aged from 45 to 65 years were divided into 3 groups depending on body mass index (BMI). Group 1 was represented by patients with AH and normal BMI, the 2 group was represented by patients with AH and excessive BMI, the 3 group was represented by patients with AH in combination with obesity. A standard clinical examination was performed, the stiffness of the vascular wall was measured by measuring the pulse wave velocity (PWV) of the muscle and elastic vessels (PWVe), vascular age was calculated, and the laboratory markers of obesity were determined.Results.High percentage of visceral obesity was observed: 20,0% among people with normal BMI, 64,4% among overweight people and 100% among people with obesity (differences between 1 and 2, 1 and 3, 2 and 3 groups are reliable). A statistically significant increase in PWVe was detected in patients with AH and obesity in comparison with patients with AH and normal body weight (9,8 [8,5; 11,3] vs 8,0 [79; 8,1] m/s). Vascular age was higher in patients with AH and overweight or obesity compared with patients with AH and normal weight (670 [60,0; 76,0], 68,0 [60,0; 72,0] vs 58,0 [57,0; 60,0] years, respectively). A statistically significant increase in the concentration of leptin (6,9 [4,5; 15,1] vs 19,0 [74; 42,7] vs 53,8 [38,4; 75,8] ng/ml) was detected, as well as a decrease in adiponectin concentration from the 1 to the 3 group (44,9 [36,6; 55,8] vs 16,5 [12,5; 24,7] vs 18,6 [15,3; 22,4] ng/ml, respectively).Correlation analysis revealed the presence of highly reliable relationships between the parameters of rigidity of the main arteries and laboratory markers of obesity.Conclusion.The results indicated a negative effect of hyperleptinemia and hypoadiponectinemia on the elasticity of the vascular wall of the main arteries and the vascular age in hypertensive patients with its combination with overweight or obesity.

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National Clinical Recommendations for Obesity: Concept and Prospects

Cited by 14 publications

References 4 publications

The effect of non-alcoholic fatty liver disease on the functional state of the kidneys in patients with chronic heart failure

The effect of non-alcoholic fatty liver disease on the functional state of the kidneys in patients with chronic heart failure

Modern methods to follow-up of obese patient

The state of the main arteries, vascular age in patients with arterial hypertension and obesity: the role of leptin and adiponectin

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