National Surgical Site Infection (SSI) surveillance: response to Jenks et al.

Lamagni, Theresa; Elgohari, Suzanne; Wloch, Catherine; Charlett, André; Harrington, Pauline; Johnson, Alan P.

doi:10.1016/j.jhin.2017.06.003

Cited by 4 publications

(2 citation statements)

References 2 publications

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“…Neurosurgical wound infection is one of the most serious complications after craniotomy, leading to poor prognosis and even death 31 . At the same time, the bacterial positive culture rate of cerebrospinal fluid is low, and early clinical diagnosis is difficult, so how to early warning and screening of high‐risk groups, and how to take targeted preventive and control measures is extremely important 32 . Therefore, it is important to identify the risk factors of post‐craniotomy wound infection as early as possible, study the occurrence of post‐craniotomy wound infection in advance, communicate with patients and their families in advance, and do a good job of prevention, which is conducive to the physical and psychological recovery of post‐craniotomy patients and improve their postoperative quality of life.…”

Section: Discussionmentioning

confidence: 99%

Risk and protective factors associated with wound infection after neurosurgical procedures: A meta‐analysis

He,

Li,

Liu

2024

International Wound Journal

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To systematically evaluate the risk factors for wound infection at the surgical site after neurosurgical craniotomy by meta‐analysis, and to provide an evidence‐based basis for preventing the occurrence of wound infection. A computerised search of PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure and Wanfang database was conducted for relevant studies on risk factors for surgical site wound infection after neurosurgical craniotomy published from the database inception to November 2023. Two researchers independently screened the literature, extracted the data and performed quality assessment in strict accordance with the inclusion and exclusion criteria. STATA 17.0 software was applied for data analysis. Overall, 18 papers with 17 608 craniotomy patients were included, of which 905 patients developed wound infections. The analysis showed that underlying diseases [OR = 2.50, 95% CI (1.68, 3.72), p < 0.001] and emergency surgery [OR = 2.47, 95% CI (1.80, 3.38), p < 0.001] were the risk factors for developing wound infections after craniotomy, age < 60 years [OR = 0.72, 95% CI (0.52, 0.98), p = 0.039] was a protective factor for wound infections; whereas sex [OR = 1.11, 95% CI (0.98, 1.27), p = 0.112] and the antimicrobial use [OR = 1.30, 95% CI (0.81 2.09), p = 0.276] were not associated with the presence or absence of wound infection after craniotomy. Underlying disease and emergency surgery are risk factors for developing wound infections after craniotomy, whereas age < 60 years is a protective factor. Clinicians can reduce the occurrence of postoperative wound infections by communicating with patients in advance about the possibility of postoperative wound infections based on these factors, and by doing a good job of preventing postoperative wound infections.

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Section: Discussionmentioning

confidence: 99%

Risk and protective factors associated with wound infection after neurosurgical procedures: A meta‐analysis

He,

Li,

Liu

2024

International Wound Journal

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“…It is challenging for clinicians to differentiate whether these patients have concomitant postoperative intracranial infections based solely on their symptoms. CSF examination is often necessary to aid in diagnosis, but the positive rate of CSF bacterial culture for CNS infection is generally low [6,7]. Moreover, the CSF indexes of patients with SAH are significantly abnormal in this pathological state due to the influence of bloody CSF, making it even more challenging to diagnose intracranial infections after craniotomy.…”

Section: Discussionmentioning

confidence: 99%

Effect of Spontaneous Subarachnoid Hemorrhage on Cerebrospinal Fluid Indicators

You

Chen

2023

Brain Sciences

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The cerebrospinal fluid (CSF) analysis in ruptured aneurysms can be greatly affected by subarachnoid hemorrhage (SAH), making the diagnosis of intracranial infection more difficult after surgery. This study aimed to identify the reference value range of CSF in the pathological state following spontaneous SAH. A retrospective analysis of demographic and CSF data of all spontaneous SAH patients treated between January 2018 and January 2023 was conducted. A total of 101 valid CSF specimen data were collected for analysis. Our results indicate that in 95% of patients after spontaneous SAH, the leukocyte count in CSF was less than 880 × 106/L. Additionally, the proportion of neutrophils, lymphocytes, and monocytes did not exceed 75%, 75%, and 15%, respectively, in 95% of the population. Furthermore, in 95% of the specimens, the concentration of chloride, glucose, and protein was >115 mmol/L, >2.2 mmol/L, and <2.3 g/L, respectively. Compared to the normal reference values, the CSF indexes after spontaneous SAH showed significant changes, especially in the leukocyte count, chloride concentration, and glucose concentration. Using “white blood cell count < 880/mm3, glucose > 2.2 mmol/L, chloride > 115” as the reference values for SAH pathological status is more meaningful for reference purposes.

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