National trends in resection of cystic lesions of the pancreas

Reames, Bradley N.; Scally, Christopher P.; Frankel, Timothy L.; Dimick, Justin B.; Nathan, Hari

doi:10.1016/j.hpb.2015.11.002

Cited by 4 publications

(4 citation statements)

References 36 publications

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“…Pancreatic fistula and wound infection were the most common complications among our patients, which is comparable to other series. The mortality and surgical complication rates of the current study were comparable with those of Reames et al (9) ; however, they were higher than those of the study carried out in 2011 by Gaujoux (10) . Both morbidity and mortality were more associated with complications of the surgical procedures and/or the clinical status of the patients than with the nature of the lesions (17) .…”

Section: Discussionsupporting

confidence: 81%

“…However, a much lower prevalence is found when analyzing only pancreatic neoplastic cystic lesions (1% to 10% of pancreatic neoplasms). These, despite their rarity, account for about 30% of pancreatic resections (2,3,(5)(6)(7)(8)(9) . The incidence of CLPs is increasing (2), mainly due to advances in imaging technology and increased access to computed tomography (CT) and magnetic resonance imaging (MRI).…”

Section: Discussionmentioning

confidence: 99%

“…In summary, the majority of the neoplastic cystic lesions (serous neoplasms, mucinous neoplasms and Frantz's tumors) were mostly observed in females, whereas pseudocysts presented no predominance and IPMNs were more common among men; Frantz's tumor predominated in young adults, whereas the others were more frequent among middle-aged to elderly individuals. Usually, the Frantz's tumor is 10 times more frequent in women (9) . Regarding the clinical presentation of patients at diagnosis, the majority (89.7%) were symptomatic, differently from what has been reported in other series with 40% to 75% of cases being asymptomatic (2)(3)(4)7,9) ; it is very likely that this was due to the fact that all individuals of this series underwent surgery and thus the surgical indication biased the results.…”

Section: Discussionmentioning

confidence: 99%

“…Usually, the Frantz's tumor is 10 times more frequent in women (9) . Regarding the clinical presentation of patients at diagnosis, the majority (89.7%) were symptomatic, differently from what has been reported in other series with 40% to 75% of cases being asymptomatic (2)(3)(4)7,9) ; it is very likely that this was due to the fact that all individuals of this series underwent surgery and thus the surgical indication biased the results. Therefore, the majority of the individuals in the current series due presented large-volume lesions diagnosed after causing mass effect and consequently abdominal pain, nausea, vomiting, weight loss and abdominal distension.…”

Section: Discussionmentioning

confidence: 99%

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Surgical Management of Cystic Lesions of the Pancreas: A Single-Centre Experience

Sia

Soares

Gestic

et al. 2018

Arq. Gastroenterol.

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BACKGROUND: Cystic lesions of the pancreas represent a group of pancreatic diseases with great histological heterogeneity, varying from benign lesions, some of them with malignant potential, to overt malignant lesions. OBJECTIVE: To describe the cases of cystic lesions of the pancreas which underwent surgical intervention at a tertiary university hospital. METHODS: This is a retrospective population-based study (historical cohort) which was carried out enrolling individuals attended at the Outpatient service of Pancreas Surgery of the Hospital de Clínicas of Unicamp. The individuals underwent surgical procedures performed from January 2012 through December 2016. RESULTS: In the period evaluated, 39 cases of cystic lesions of the pancreas which underwent surgery were identified, 26 (66.6%) of which were female. The average age at diagnosis was 47.4±16.4 years (range, 18-73). In regards to symptoms, 35 (89.7%) were symptomatic. The average length of hospital stay was 10 days (range 4-76). Surgeries performed to treat the lesions depended on the localization and type of the lesions: cystojejunostomy (41%), distal pancreatectomy (36%), pancreaticoduodenectomy (15.4%), drainage of ruptured and/or infected pseudocyst (5.2%) and central pancreatectomy (2.6%). CONCLUSION: Cystic lesions of the pancreas are a group of lesions with a highly varying presentation and diagnostic approach and may require an also highly variable surgical treatment. An appropriate preoperative imaging diagnosis is essential for their management.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Surgical Management of Cystic Lesions of the Pancreas: A Single-Centre Experience

Sia

Soares

Gestic

et al. 2018

Arq. Gastroenterol.

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Natural History of Pancreatic Cysts

Larson

Kwon

2017

Dig Dis Sci

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Pancreatic cystic neoplasms are discovered with increasing frequency. Accurate knowledge of the natural history of cystic neoplasms is crucial to develop useful and cost-effective strategies for surveillance and surgical resection. To date, the natural history of cystic neoplasms is still incomplete due to lack of adequate diagnostic accuracy in the absence of surgical pathology. Nevertheless, current evidence points to risk factors for malignant transformation to help clinical management. New biomarkers that accurately distinguish cyst neoplasms and those most likely to progress to cancer would help clarify the natural history of cystic neoplasms.

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