Natural gum as bio-reductant to green synthesize silver nanoparticles: assessing the apoptotic efficacy on MCF-7 and SH-SY5Y cell lines and their antimicrobial potential

Hashemabadi, Mohammad; Haghighi, S; Amandadi, Mojdeh; Mohammadinejad, Reza; Farnoosh, Gholamreza; Azimzadeh, Mostafa; Taheri, Ramezan Ali

doi:10.1007/s00289-020-03238-9

Cited by 10 publications

(5 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The preparation of AgNPs can be achieved by various techniques. Among the techniques, the green synthesis of AgNPs is more ecofriendly than other methods because of the use of materials with low toxicity [ 17 – 19 ]. Several bio-based compounds such as terpenoids, glycosides, alkaloids, and phenolics can be used as bio-reducing agents [ 10 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Green-synthesized silver nanoparticle coating on paper for antibacterial and antiviral applications

et al. 2022

View full text Add to dashboard Cite

The use of active packaging has attracted considerable attention over recent years to prevent and decrease the risk of bacterial and viral infection. Thus, this work aims to develop active packaging using a paper coated with green-synthesized silver nanoparticles (AgNPs). Effects of different silver nitrate (AgNO 3 ) concentrations, viz. 50, 100, 150, and 200 mM (AgNPs-50, AgNPs-100, AgNPs-150, and AgNPs-200, respectively), on green synthesis of AgNPs and coated paper properties were investigated. A bio-reducing agent from mangosteen peel extract (ex-Garcinia mangostana (GM)) and citric acid as a crosslinking agent for a starch/polyvinyl alcohol matrix were also used in the synthetic process. The presence of AgNPs, ex-GM, and citric acid indicated the required synergistic antibacterial activities for gram-positive and gram-negative bacteria. The paper coated with AgNPs-150 showed complete inactivation of virus within 1 min. Water resistance and tensile strength of paper improved when being coated with AgNPs-150. The tensile strength of the coated paper was found to be in the same range as that of a common packaging paper. Result revealed that the obtained paper coated with AgNPs was proven to be effective in antibacterial and antiviral activities; hence, it could be used as an active packaging material for items that require manual handling by a number of people.

show abstract

Section: Introductionmentioning

confidence: 99%

Green-synthesized silver nanoparticle coating on paper for antibacterial and antiviral applications

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Anthocyanins, from the subclass of flavonoids, are a significant part of phenolic compounds and form red, blue, and purple pigments in plants 49 . Noteworthy, there is evidence showing the cytotoxicity of green synthesized silver nanoparticles against SH-SY5 cells 50 , though our observations indicated the harmlessness of the nanoparticles toward the cells, especially at low concentrations.…”

Section: Discussionmentioning

confidence: 50%

Neuroprotective activity of green synthesized silver nanoparticles against methamphetamine-induced cell death in human neuroblastoma SH-SY5Y cells

Khorrami

Dogani

Esmaeili‐Mahani

et al. 2023

Sci Rep

Self Cite

View full text Add to dashboard Cite

The present study aimed to investigate the neuroprotective activity of the black peel pomegranate extract, and silver nanoparticles (AgNPs) biosynthesized using the extract. We pretreated the human neuroblastoma SH-SY5 cells with the extract and AgNPs and evaluated the neuroprotective activity of these agents against methamphetamine (Meth) cytotoxicity. The NPs were spherical with 19 ± 8 nm size, − 28 mV surface charge, and 0.20 PDI. Meth killed the cells by increasing proapoptotic (Bax, PTEN, AKT, PI3K, NF-κB, P53, TNF-α, Cyt C, and Cas 3) and decreasing the antiapoptotic genes (Bcl-2) expression. Exposure to Meth caused DNA fragmentation and increased the intercellular ROS and malondialdehyde (MDA) levels while reducing the mitochondrial membrane potential (MMP). A 4-h pretreatment of the cells with the extract and AgNPs could retain the viability of the cells above 80% by increasing the Bcl-2 expression up to fourfold and inhibiting the cell death pathways. ROS, MDA, and MMP levels in the pretreated cells were close to the control group. The percentage of necrosis in cells pretreated with the extract and AgNPs declined to 32% and 8%, respectively. Our promising findings indicated that AgNPs could reduce Meth-induced oxidative stress and prevent necrotic and apoptotic cell death by regulating related genes’ expression.

show abstract

“…Recently, have been reported new biopolymers such as gum exudates in the encapsulation process [135,136]. Gum arabic is an exudation of plant from Acacia seyal and Acacia Senegal trees.…”

Section: Gum Arabicmentioning

confidence: 99%

Biopolymers for Biological Control of Plant Pathogens: Advances in Microencapsulation of Beneficial Microorganisms

et al. 2021

Self Cite

View full text Add to dashboard Cite

The use of biofertilizers, including biocontrol agents such as Pseudomonas and Bacillus in agriculture can increase soil characteristics and plant acquisition of nutrients and enhancement the efficiency of manure and mineral fertilizer. Despite the problems that liquid and solid formulations have in maintaining the viability of microbial agents, encapsulation can improve their application with extended shelf-life, and controlled release from formulations. Research into novel formulation methods especially encapsulation techniques has increased in recent years due to the mounting demand for microbial biological control. The application of polymeric materials in agriculture has developed recently as a replacement for traditional materials and considered an improvement in technological processes in the growing of crops. This study aims to overview of types of biopolymers and methods used for encapsulation of living biological control agents, especially microbial organisms.

show abstract

Natural gum as bio-reductant to green synthesize silver nanoparticles: assessing the apoptotic efficacy on MCF-7 and SH-SY5Y cell lines and their antimicrobial potential

Cited by 10 publications

References 60 publications

Green-synthesized silver nanoparticle coating on paper for antibacterial and antiviral applications

Green-synthesized silver nanoparticle coating on paper for antibacterial and antiviral applications

Neuroprotective activity of green synthesized silver nanoparticles against methamphetamine-induced cell death in human neuroblastoma SH-SY5Y cells

Biopolymers for Biological Control of Plant Pathogens: Advances in Microencapsulation of Beneficial Microorganisms

Contact Info

Product

Resources

About