2021
DOI: 10.1016/j.neubiorev.2020.12.001
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Natural products improve healthspan in aged mice and rats: A systematic review and meta-analysis

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Cited by 16 publications
(18 citation statements)
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“…Furthermore, C. elegans offers numerous human disease-specific strains (Markaki and Tavernarakis 2020) and is frequently used to pre-screen compounds for their later pharmaceutical usage (Chen et al 2015;Dengg and van Meel 2004;Matsunami 2018;Papaevgeniou and Chondrogianni 2018) and also reviewed in Kim et al (2017). An additional systematic review focusing on healthspan in rodents was recently published (Musillo et al 2021).…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, C. elegans offers numerous human disease-specific strains (Markaki and Tavernarakis 2020) and is frequently used to pre-screen compounds for their later pharmaceutical usage (Chen et al 2015;Dengg and van Meel 2004;Matsunami 2018;Papaevgeniou and Chondrogianni 2018) and also reviewed in Kim et al (2017). An additional systematic review focusing on healthspan in rodents was recently published (Musillo et al 2021).…”
Section: Introductionmentioning
confidence: 99%
“…Ultimately, in order to assess the effects of natural compounds, such as curcuma, we need to refine our ability to measure health (and the lack of) in a life-long perspective and to characterize the conditions for the transition from health to disease [ 39 , 73 , 135 ].…”
Section: Discussionmentioning
confidence: 99%
“…Preclinical animal models have clearly shown a main effect of natural compounds, including curcumin, on cognitive function during ageing [ 26 , 36 , 37 , 38 , 39 ]. These effects are most likely related to the ability of curcumin to act directly on Aβ plaques as well as to its anti-inflammatory and antioxidant properties.…”
Section: Curcumin Cognitive Decline and Glucose Homeostasis (Peripheral And Central Actions)mentioning
confidence: 99%
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