Naturally occurring organobromine compounds (OBCs) including polybrominated dibenzo-p-dioxins in the marine sponge Hyrtios proteus from The Bahamas

Wu, Qiong; Eisenhardt, Natalie; Holbert, Stephanie Shaw; Pawlik, Joseph R.; Kucklick, John R.; Vetter, Walter

doi:10.1016/j.marpolbul.2021.112872

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Natural Product Reports Review1

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Cited by 5 publications

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“…This study highlighted the role marine animals may have in biomagnication of halogenated compounds in the trophic chain. 523 A study has compared the geographic and phylogenetic distribution of a cryptic Ribosomally synthesised and Posttranslationally modied Peptide (RiPP) halogenating enzyme in widespread sponge metagenomes across the Pacic and Atlantic oceans. More than 50 copies of BGCs encoding for RiPP halogenases across multiple bacterial taxa were detected in various sponge holobionts, highlighting the cosmopolitan nature of the BGC, which is at odds with the cryptic nature of the halogenated RiPPs they would produce.…”

Section: Natural Product Reports Reviewmentioning

confidence: 99%