Naturally Occurring Steroids

Marwat, G. A.; Khan, A. R.; Hussain, Ibrar; Kalsoom, Saima

doi:10.1002/chin.200716243

Cited by 3 publications

(3 citation statements)

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“…Almost all steroid molecules possess the same basic perhydroxyl cyclopentenophenanthrene skeleton. The differences in the basic skeleton and the attachment of different groups result in various classes of steroids [ 17 ]. Steroids have many pharmacological applications and the research is continuing to find out about these metabolites, as potential lead compounds in drug design and discovery [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

Bioactive Steroids and Saponins of the Genus Trillium

et al. 2017

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The species of the genus Trillium (Melanthiaceae alt. Trilliaceae) include perennial herbs with characteristic rhizomes mainly distributed in Asia and North America. Steroids and saponins are the main classes of phytochemicals present in these plants. This review summarizes and discusses the current knowledge on their chemistry, as well as the in vitro and in vivo studies carried out on the extracts, fractions and isolated pure compounds from the different species belonging to this genus, focusing on core biological properties, i.e., cytotoxic, antifungal and anti-inflammatory activities.

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Section: Introductionmentioning

confidence: 99%

Bioactive Steroids and Saponins of the Genus Trillium

et al. 2017

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“…This showed that the whole Cassia ferruginea (Schrad D.C) root is rich in chemical constituents as investigated in this study. These principles have been known for many years to exhibit biological activity, such as effects on the central nervous system, and antibacterial, antiturmour, and anthehelmintic activity Thus, the presence of these phyto-constituents in the Cassia ferruginea (Schrad D.C) root bark and root core such as alkaloids which act as antiparasitic and treating gout [33]; tannins act against diarrhea [34]; steroid compounds as hormone stimulator and regulator [35]; and in the treatment of prostate cancer [36]; Saponins as anti-inflammatory, hypocholesterolemic and immune stimulating [37]; flavonoid prevent ulcer [38]; cardiac glycoside as potential anticancer [39]]; and phenolic compound possess anti-cancer ability [40] has indeed support the acclaimed wonders and their various uses traditionally. Thus, natural agent such as, water, the sun, air and Phytochemical constituents (medicinal herbs) which are gotten from healthy food, as well as the adoption of healthy habits (physical exercise, adequate rest, good mental health and trust in God) may do more for health than all powerful, chemically synthesized medicines or aggressive treatment.…”

Section: Fig-7: Phytochemical Screenings Results (Foam Test) Results mentioning

confidence: 99%

Comparative Phyto-Constituents Analysis from the Root Bark and Root Core Extractives of Cassia ferruginea (Schrad D. C) Plant

Y¹,

Isah²,

M.S³

2016

SJAVS

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Abstract:In an attempt to investigate the phyto-constituents present in the root bark and root core of Cassia ferruginea (Schrad D.C) plant due to acclaimed medicinal wide range uses of the plant especially for mental illness, sexual dysfunction and microbial infections, both the root bark and root core of Cassia ferruginea (Schrad D.C) plant were collected, processed and extracted using 95% ethanol. Phytochemical analysis method was used to determine the various constituents present qualitatively. The study revealed the presence of Alkaloids, Tannin, Saponins, Phenols, Flavonoid, and Cardiac glycosides in both root bark and the root core sample, in addition to Protein, Quinone, and Coumarins in the root bark except for steroid which was only present in the root core of Cassia ferruginea (Schrad D.C) plant. The study has shown the nature distribution of phyto-constituents in plant at different parts, no matter how close the parts are. As, such all the parts of plant are necessary to be considered useful as its contained different components.

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“…A steroid is a group of secondary metabolites derived from cholesterol; it has diverse chemical structure molecules possess the same basic perhydroxylcyclopentenophenathrene skeleton [16]. The differences in the basic skeleton and the attachment of different groups result in various classes of steroids [17]. Steroids have many pharmacological applications and research is continuing to find the other applications of the compound in drug design and discovery [18].…”

Section: Discussionmentioning

confidence: 99%

Proximate and phytochemical composition of Phyllantus amarus

Achikanu¹,

Ujah²,

Ezenwali³

2022

World J. Adv. Res. Rev.

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This study aimed to determine the proximate and phytochemical composition ofPhyllanthusamarus. The results of proximate composition of Phyllanthusamarus showed that the plant leaves contains fat 8.40 %, moisture 6.48 %, ash 10.58 %, fibre 2.40 %, protein 23.97 % and carbohydrate 48.02 %. The results of phytochemical composition of Phyllanthusamarus revealed Kaempferol 2.3726 ug/ml, Steroid 15.7626 ug/ml, Proanthocyandin 8.1619 ug/ml, Catechin 23.3542 ug/ml, Anthocyanin 3.8979 ug/ml, Narigenin 13.5721 ug/ml, Dihydrocytisine 8.0184 ug/ml, Cyanogenic glycoside 8.7028 ug/ml, Aphyllidine 0.2959 ug/ml, Ammodendrine 6.2495 ug/ml, Tannin 9.8090 ug/ml, Flavonoes 8.7210 ug/ml, Cardiac glycoside 14.2203 ug/ml, Flavone 3.60099 ug/ml, Ribalinidine 10.1874 ug/ml, Spartein 4.1965 ug/ml, Phytate 8.1192 ug/ml, Oxalate 9.0074 ug/ml, Epihedrine 1.9501 ug/ml, Sapogenine 18.0269 ug/ml. It may be concluded that the leaves of Phyllanthusamarus contain several phytochemicals that could be of good therapeutic purposes.

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Naturally Occurring Steroids

Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Cited by 3 publications

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Bioactive Steroids and Saponins of the Genus Trillium

Bioactive Steroids and Saponins of the Genus Trillium

Comparative Phyto-Constituents Analysis from the Root Bark and Root Core Extractives of Cassia ferruginea (Schrad D. C) Plant

Proximate and phytochemical composition of Phyllantus amarus

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