Nd:YAG and pulsed dye laser therapy in infantile haemangiomas: a retrospective analysis of 271 treated haemangiomas in 149 children

Abstract

Combined Nd:YAG/PDL therapy is an effective and well-tolerated local treatment option for IH of any classification, in any phase of development and at any age. With regard to the systemic use of propranolol, combined Nd:YAG/PDL therapy seems a safe and promising alternative in many cases.

Combination therapy of oral propranolol and combined Nd:YAG/pulsed dye laser therapy in infantile hemangiomas: a retrospective analysis of 48 treated hemangiomas in 30 children

“…Group A: parallel treatment with propranolol and laser therapy Simultaneous propranolol and laser therapy achieved a strong improvement (IV) of the findings in 10/11 (90.9 %) children. An earlier study in 137 children reported strong improvement in 72.2 % of those IH treated with Nd:YAG/PDL combination therapy [41]. Response rates in propranolol treatment are comparable to those in Nd:YAG/PDL combination therapy [8].…”

“…Group B: Propranolol first, followed by laser therapy Recurrent IH after initially successful propranolol treatment occurs in up to 25 % of treated children, and in 10-15 % of these, repeat treatment with propranolol is required [8,[27][28][29]. In contrast, recurrence after initially successful laser therapy is rare (2 % according to our own studies) [41]. In this earlier study, non-response to laser therapy requiring subsequent propranolol treatment was seen in 3.6 % of cases [41].…”

“…It is however mainly effective in proliferating IH [8,48]. In contrast, Nd:YAG/PDL therapy is effective both during the proliferation phase and the involution phase of IH of varying extent [39,41]. Initiation of propranolol treatment is recommended in children aged five weeks to five months [49], while laser therapy may be performed at any age [41].…”

“…In contrast, Nd:YAG/PDL therapy is effective both during the proliferation phase and the involution phase of IH of varying extent [39,41]. Initiation of propranolol treatment is recommended in children aged five weeks to five months [49], while laser therapy may be performed at any age [41]. It therefore Figure 1 Representative clinical results of group A (concomitant propranolol and combined Nd:YAG/pulsed dye laser therapy).…”

Therapie infantiler Hämangiome

“…Dabei wurden (vor Zulassung von Propranolol) 149 Kinder mit insgesamt 271 Hämangiomen lasertherapiert, davon 137 Kinder mit 187 Hämangiomen mit der Neodym:YAG‐Farbstofflaser‐Kombinationstherapie. An diesem Kollektiv wurde gezeigt, dass die Neodym:YAG‐Farbstofflaser‐Kombinationstherapie bei jeder Form infantiler Hämangiome (superfiziell, subkutan, gemischt), in jeder Entwicklungsphase des Hämangioms (Proliferation und Regression) und in jedem Kindesalter effektiv ist .…”