Near-Field Interaction of a Jet with Leading-Edge Vortices

Wang, Frank Y.; Proot, Michael M. J.; Charbonnier, Jean-Marc; Sforza, Pasquale M.

doi:10.2514/2.2700

Cited by 14 publications

(9 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most likely reason behind this improvement is that the trailing-edge jet creates a favorable pressure gradient near the trailing-edge 20 and reduces the adverse pressure gradient due to the fin. However, there are other factors such as entraintment effects suggested by Reference 19 and the interaction between the jet and the wing vortices 25 . Wang et al 25 showed that wing vortices may be drawn toward the jet center by the induced velocity created by the jet vortices.…”

Section: Water Tunnel Experimentsmentioning

confidence: 97%

Pharmacogenetic Factors Contributing to Variation in Response to Tamoxifen and Raloxifene

Raftogianis¹

2001

View full text Add to dashboard Cite

'Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to Washington Headquarters Services, Directorate AUTHOR(S)Rebecca B. Raftogianis, Ph.D. FUNDING NUMBERSDAMD17-00-1-0248 The purpose of these studies is to elucidate the pharmacogenetic factors that contribute to variation in human response to tamoxifen (TAM) and raloxifene (RAL). We had previously identified and partially characterized common genetic polymorphisms in two human drug -metabolizing genes, SULT1A1 and UGT1A1. We hypothesized that these polymorphisms contributed to variation in TAM or RAL metabolism. These studies were divided into three aims with the purpose of 1) biochemically characterizing the contribution of these enzymes to the metabolism of TAM and RAL; 2) developing cell model systems to study allele-specific differences in cellular response to these molecules and; 3) perform a clinical pharmacogenetic study to evaluate the association of common genetic polymorphisms in drug metabolizing genes with variable clinical response to TAM. Thus far we have determined that SULT1A1 and UGT1A6 contributed to the inactivation of 4-hydroxytamoxifen (OHT), the active metabolite of TAM, and that a separate enzyme, UGT1A9 catalyzed the glucuronidation of RAL. We established MCF-7 breast cancer cell lines stably expressing the wildtype and variant SULT1A1 alleles and have measured allele-specific differences in the response of these cells to estrogens and OHT. These studies suggest that pharmacogenetic factors might contribute to variable cellular response to antiestrogens. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES)

show abstract

Section: Water Tunnel Experimentsmentioning

confidence: 97%

Pharmacogenetic Factors Contributing to Variation in Response to Tamoxifen and Raloxifene

Raftogianis¹

2001

View full text Add to dashboard Cite

show abstract

“…Therefore, significant effects on the aerodynamic forces and moments on the wings are expected. The importance of the effects of the entrainment process and the interaction between the jet and wing vortices were reported [14,15]. Force measurements [13] revealed that the effect of nozzle geometry can be important because the entrainment effect of the jet depends on it.…”

Section: Introductionmentioning

confidence: 96%

Effects of Unsteady Trailing-Edge Blowing on Delta Wing Aerodynamics

Jiang

Wang

Gursul

2010

Journal of Aircraft

View full text Add to dashboard Cite

The effects of unsteady trailing-edge blowing on delta wing aerodynamics were investigated experimentally to understand the aerodynamics-propulsion interaction for dynamic thrust vectoring. Two models with sweep angles of 50 and 65 deg, representing nonslender and slender delta wings, respectively, were tested in a water tunnel. Flow visualization and velocity and force measurements were conducted at stall and poststall incidences. For the periodic blowing, it was found that the dynamic response of leading-edge vortex breakdown and wing normal force coefficient exhibit phase lags for both nonslender and slender delta wings. The estimated time constants are larger than those reported in the literature for unsteady wings undergoing pitching or plunging. In the case of transient blowing, the time delay for the decelerating jet is significantly larger than that for the accelerating jet. The variation of the circulation and the reattachment process near the wing surface were studied by means of velocity measurements. The range of the estimated time constants is similar at the stall and poststall incidences for both the slender and nonslender wings.= dimensionless frequency, fc=U 1 q = freestream dynamic pressure Re = Reynolds number S w = wing surface area s = local semispan T = period t = wing thickness or time U jet = jet velocity U 1 = freestream velocity u = velocity X bd = distance from wing apex to leading-edge vortex breakdown location y jet = spanwise location of jet = wing incidence = jet pitch angle = circulation X bd = peak-to-peak amplitude of the variation of the vortex breakdown location = leading-edge sweep angle = fluid kinematic viscosity = air density = time constant = phase lag ! = angular frequency ! x = streamwise vorticity

show abstract

“…Wang et al 1 in 2000 presented their low-speed study on the evolution of a jet in the vortex wake of a simple delta wing. Laser lightsheet visualizations were performed for three planform angleof-attack cases, that is, 5, 15, and 25 deg, and for three stations at distances up to 111 jet diameters downstream.…”

Section: Introductionmentioning

confidence: 99%

“…To isolate the in uence of the vortex wake itself on the evolving plume, the orientationof the jet was xed parallelto the freestreamdirection instead of varying with the planform's angle of attack. 1 The angle of attack and the jet-to-freestream velocity ratio were varied, and the associated three-dimensional ow eld was measured. Key results of the investigation are presented in the following.…”

Section: Introductionmentioning

confidence: 99%

Aerodynamics of a Jet in the Vortex Wake of a Wing

Wang

Zaman

2002

AIAA Journal

Self Cite

View full text Add to dashboard Cite

Results of a low-speed experimental investigation of jet behavior in the trailing vortex wake of a wing are presented. The effects of varying jet-to-freestream velocity ratio and vortex-wake strength on the downstream evolution of the ow eld are quanti ed via three-dimensional hot-wire anemometry surveys. Under conditions encountered in powered ight, especially ow states characteristics of takeoff, landing, and maneuvering of a vehicle, the jet is found to undergo severe distortion within a very short distance from the nozzle exit. The interaction of the jet and the wing vortices generates additional vortical structures. Spreading and decay of the jet are shown to be governed predominantly by the interaction of the vortices. Nomenclature D = jet diameter U jet = jet bulk velocity U 1 = freestream velocity u, v, w = axial, transverse, and spanwise velocity components u 02 , v 02 , w 02 = mean squared axial, transverse, and spanwise velocity uctuations X , Y , Z = axial, transverse, and spanwise directions of Cartesian coordinates ® = planform angle of attack 0 = circulation ! X = axial vorticity

show abstract

Near-Field Interaction of a Jet with Leading-Edge Vortices

Cited by 14 publications

References 17 publications

Pharmacogenetic Factors Contributing to Variation in Response to Tamoxifen and Raloxifene

Pharmacogenetic Factors Contributing to Variation in Response to Tamoxifen and Raloxifene

Effects of Unsteady Trailing-Edge Blowing on Delta Wing Aerodynamics

Aerodynamics of a Jet in the Vortex Wake of a Wing

Contact Info

Product

Resources

About