Near-infrared heat lamp therapeutic effect on paraoxonase 1 and myeloperoxidase as potential biomarkers of redox state changes induced by γ-irradiation in albino rats

Abdel‐Magied, Nadia; Ahmed, Amal G; Shedid, Shereen M.

doi:10.1016/j.jphotobiol.2018.01.009

Cited by 3 publications

(1 citation statement)

References 45 publications

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“…Previous study reported that oxidative low-density lipoprotein (LDL) is frequently found in the absence of monocyte/macrophages, whereas the opposite is rare, suggesting that intimal LDL accumulation and oxidation contributes to monocyte recruitment in vivo [9]. Furthermore, near-infrared heat lamp therapy for a short time can effectively prevent the lipid disorders induced by radiation through the positive modulation mechanism of paraoxonase 1 (PON1) and myeloperoxidase (MPO) enzymes and improvement of oxidative stress [10]. We believe that FIRT is useful not only for improving AVF patency but also for preventing vascular disease complications.…”

Section: Discussionmentioning

confidence: 99%

Far-infrared therapy for secondary vascular access patency of hemodialysis patients

Nakata

Aoyama

et al. 2019

Ren Replace Ther

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Introduction: Far-infrared radiation therapy (FIRT), which utilizes an invisible electromagnetic wave, has demonstrated its ability to improve vascular access flow for hemodialysis (HD) patients. Although previous overseas studies revealed the beneficial effects of FIRT on HD patients by improving vascular function, no study in Japan has examined the clinical efficacy of FIRT for such patients. Therefore, we aimed to evaluate the usefulness of FIRT for HD patients. We paid particular attention on secondary vascular access (VA) patency of HD patients. Methods: Eighteen patients who had undergone vasodilation of VA vessels or vascularization more than once were selected from approximately 70 outpatients receiving HD in the Dialysis Unit of the Juntendo University Hospital. FIRT was administered for 40 min during HD three times per week for 1 year to the not frequent VA treatment (nf-VAT) group, for which VA intervention had been performed no more than two times during the 1 year, and to the frequent VA treatment (f-VAT) group, for which VA intervention had been performed three times or more over the 1 year. Variables including VA treatment interval were compared between those groups. Results: The nf-VAT group did not require VA re-treatment during the study period. The VA treatment interval was significantly prolonged in the f-VAT group. The fistula diameter expanded, and intimal thickening improved significantly in the nf-VAT group. Oxidized low-density lipoprotein cholesterol levels decreased slightly. Conclusion: This study suggested that FIRT is effective for improving secondary VA patency. Trial registration: UMIN, UMIN000011965.

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Section: Discussionmentioning

confidence: 99%

Far-infrared therapy for secondary vascular access patency of hemodialysis patients

Nakata

Aoyama

et al. 2019

Ren Replace Ther

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Ameliorative effect of kefir against γ-irradiation induced liver injury in male rats: impact on oxidative stress and inflammation

Ali

Amin

Fattah

et al. 2020

Environ Sci Pollut Res

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The influence of near-infrared therapy on arteriovenous fistula patency in haemodialysis patients: A multicentre, randomised, controlled clinical trial

Chunyan,

Zhenbin,

Weiyi

et al. 2024

J Vasc Access

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Background: Arteriovenous fistula (AVF) is the preferred vascular access for patients undergoing haemodialysis (HD). AVF malfunction remains a major clinical problem and is a significant independent risk factor for death. Although far-infrared (FIR) therapy has been shown to reduce complications and improve the patency rate of AVFs in various studies, it has been cautiously recommended by the Kidney Disease Outcome Quality Initiative (KDOQI) guidelines for AVF care due to insufficient evidence. Therefore, it is necessary to identify more effective methods for preventing AVF dysfunction. Many in vitro studies and few clinical studies have examined the effects of near-infrared (NIR) therapy on the vasculature. This study will examine the effects of NIR therapy on AVF. Methods: A randomised, controlled, open-label, multicentre trial will compare the effect of NIR on AVF patency after 1 year of therapy with that of a control group of patients with existing AVF. One group of patients received NIR treatment above their AVFs, whereas the control group received regular care. The primary outcome is the primary fistula patency rate within 12 months. In addition, acute changes in inflammatory, vasodilatory and haemodynamic parameters after a single treatment in the first 40 participants will be examined. This study was registered in the Clinical Trials Registry (ChiCTR2300071305) at https://register.clinicaltrials.gov/ . Discussions: This study will explore the long-term and acute effects of NIR on AVFs. The study findings will provide information that can be used to develop new technical support for the prevention of AVF dysfunction in patients undergoing haemodialysis.

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Near-infrared heat lamp therapeutic effect on paraoxonase 1 and myeloperoxidase as potential biomarkers of redox state changes induced by γ-irradiation in albino rats

Cited by 3 publications

References 45 publications

Far-infrared therapy for secondary vascular access patency of hemodialysis patients

Far-infrared therapy for secondary vascular access patency of hemodialysis patients

Ameliorative effect of kefir against γ-irradiation induced liver injury in male rats: impact on oxidative stress and inflammation

The influence of near-infrared therapy on arteriovenous fistula patency in haemodialysis patients: A multicentre, randomised, controlled clinical trial

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